sodium hydroxide in methanol T=120°C; 7 h;

1: With sodium hydroxide in methanol T=20 - 120°C; Sealed tube; 2: With trifluoroacetic acid in water; acetonitrile 3: With sodium hydroxide in methanol

1: caesium carbonate / acetonitrile / 5 h / |Reflux 2: nonafluoro-n-butanesulfonyl fluoride; N-ethyl-N,N-diisopropylamine; triethylamine tris(hydrogen fluoride) / tetrahydrofuran / 48 h / 20 °C 3: triethylsilane; palladium dichloride / ethanol / 20 - 98 °C / |Inert atmosphere 4: lithium borohydride / tetrahydrofuran; ethanol / 0 - 20 °C 5: sodium hydroxide / methanol / 20 - 120 °C / |Sealed tube View Scheme

1: AlCl3, aluminium chloride / dichloromethane / 0 - 20 °C 2: caesium carbonate / acetonitrile / 5 h / |Reflux 3: nonafluoro-n-butanesulfonyl fluoride; N-ethyl-N,N-diisopropylamine; triethylamine tris(hydrogen fluoride) / tetrahydrofuran / 48 h / 20 °C 4: triethylsilane; palladium dichloride / ethanol / 20 - 98 °C / |Inert atmosphere 5: lithium borohydride / tetrahydrofuran; ethanol / 0 - 20 °C 6: sodium hydroxide / methanol / 20 - 120 °C / |Sealed tube View Scheme

1: nonafluoro-n-butanesulfonyl fluoride; N-ethyl-N,N-diisopropylamine; triethylamine tris(hydrogen fluoride) / tetrahydrofuran / 48 h / 20 °C 2: triethylsilane; palladium dichloride / ethanol / 20 - 98 °C / |Inert atmosphere 3: lithium borohydride / tetrahydrofuran; ethanol / 0 - 20 °C 4: sodium hydroxide / methanol / 20 - 120 °C / |Sealed tube View Scheme

1: triethylsilane; palladium dichloride / ethanol / 20 - 98 °C / |Inert atmosphere 2: lithium borohydride / tetrahydrofuran; ethanol / 0 - 20 °C 3: sodium hydroxide / methanol / 20 - 120 °C / |Sealed tube View Scheme

1: lithium borohydride / tetrahydrofuran; ethanol / 0 - 20 °C 2: sodium hydroxide / methanol / 20 - 120 °C / |Sealed tube View Scheme