反应条件
1: 1.) p-toluene-sulfonic acid monohydrate; 2.) hydrogen / 2.) PtO2 / 1.) benzene, reflux, 2.5 h; 2.) ethanol, 2.5 atm.
2: hydrogen / 10 percent Pd-on-charcoal / ethanol / 4 h / 1520 Torr
View Scheme
参考文献
Horn; Dijkstra; Mulder; et al.
European Journal of Medicinal Chemistry, 1981 , vol. 16, # 5 p. 469 - 472