(4-羟基-1-哌啶基)(苯基)甲酮合成路线 （共 12 条）
反应条件
1: With copper(I) bromide in acetonitrile T=20°C; 0.05 h; Inert atmosphere; 2: With 1,2-bis(1,1-dimethylethyl)-3-diaziridinone in acetonitrile T=60°C; 5 h;
参考文献
Zhu, Yingguang; Zhao, Baoguo; Shi, Yian
Organic Letters, 2013 , vol. 15, # 5 p. 992 - 995
反应条件
sodium carbonate in water
参考文献
Kyowa Hakko Kogyo Co., Ltd.
Patent: US4448964 A1, 1984 ;
反应条件
sodium tetrahydroborate in methanol
T=20°C; 3 h;
参考文献
Barbe, Guillaume; Charette, Andre B.
Journal of the American Chemical Society, 2008 , vol. 130, # 1 p. 18 - 19
反应条件
Aspergillus niger in growing culture;
参考文献
Parshikov, I.A.; Modyanova, L.V.; Dovgilivich, E.V.; Terent'ev, P.B.; Vorob'eva, L.I.; Grishina, G.V.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1992 , vol. 28, # 2 p. 159 - 162
Khimiya Geterotsiklicheskikh Soedinenii, 1992 , # 2 p. 195 - 199
反应条件
triethylsilane; NaPF6; dirhenium heptaoxide in dichloromethane
T=50°C; 12 h; chemoselective reaction;
参考文献
Das, Braja Gopal; Ghorai, Prasanta
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 26 p. 4379 - 4382
反应条件
in dichloromethane
T=-10°C;
参考文献
Murahashi, Shun-ichi; Naota, Takeshi; Nakajima, Nobuyuki
Tetrahedron Letters, 1985 , vol. 26, # 7 p. 925 - 928
反应条件
1: 87 percent / t-BuOOH, RuCl2(PPh3)3 / 3 h / other cyanohydrins
2: 95 percent / CH2Cl2 / Ambient temperature
View Scheme
参考文献
Murahashi; Naota
Russian Journal of Organic Chemistry, 1996 , vol. 32, # 2 p. 203 - 213
反应条件
1: 1.) NaHSO3
2: 87 percent / t-BuOOH / RuCl2(PPh3)3 / benzene / 3 h / Ambient temperature; Var. Ru complexes, oxidants and solvents
3: 99 percent / CH2Cl2 / -10 °C
View Scheme
参考文献
Murahashi, Shun-ichi; Naota, Takeshi; Nakajima, Nobuyuki
Tetrahedron Letters, 1985 , vol. 26, # 7 p. 925 - 928
反应条件
1: thionyl chloride; N,N-dimethyl-formamide / dichloromethane
2: triethylamine / dichloromethane / -10 - 20 °C
View Scheme
参考文献
Yu, Xiaolong; Yang, Tao; Wang, Shulin; Xu, Hailiang; Gong, Hegui
Organic Letters, 2011 , vol. 13, # 8 p. 2138 - 2141
反应条件
1: water; potassium carbonate; chloroform
2: Raney nickel; ethanol / 75 °C / 113268 Torr / Hydrogenation
View Scheme
参考文献
McElvain; McMahon
Journal of the American Chemical Society, 1949 , vol. 71, p. 901,904
