(5-氨基-2-甲基苯基)(苯基)甲酮合成路线 （共 5 条）
反应条件
hydrogen; Lindlar's catalyst in tetrahydrofuran
T=20°C;
参考文献
Gobbi, Silvia; Cavalli, Andrea; Negri, Matthias; Schewe, Katarzyna E.; Belluti, Federica; Piazzi, Lorna; Hartmann, Rolf W.; Recanatini, Maurizio; Bisi, Alessandra
Journal of Medicinal Chemistry, 2007 , vol. 50, # 15 p. 3420 - 3422
反应条件
1: 51 percent / KNO3; H2SO4 / 0 °C
2: SOCl2 / 2 h / 80 °C
3: 1.8 g / AlCl3 / 20 °C
4: 76.5 percent / H2 / Pd/CaCO3 / tetrahydrofuran / 20 °C
View Scheme
参考文献
Gobbi, Silvia; Cavalli, Andrea; Negri, Matthias; Schewe, Katarzyna E.; Belluti, Federica; Piazzi, Lorna; Hartmann, Rolf W.; Recanatini, Maurizio; Bisi, Alessandra
Journal of Medicinal Chemistry, 2007 , vol. 50, # 15 p. 3420 - 3422
反应条件
1: SOCl2 / 2 h / 80 °C
2: 1.8 g / AlCl3 / 20 °C
3: 76.5 percent / H2 / Pd/CaCO3 / tetrahydrofuran / 20 °C
View Scheme
参考文献
Gobbi, Silvia; Cavalli, Andrea; Negri, Matthias; Schewe, Katarzyna E.; Belluti, Federica; Piazzi, Lorna; Hartmann, Rolf W.; Recanatini, Maurizio; Bisi, Alessandra
Journal of Medicinal Chemistry, 2007 , vol. 50, # 15 p. 3420 - 3422
反应条件
1: 1.8 g / AlCl3 / 20 °C
2: 76.5 percent / H2 / Pd/CaCO3 / tetrahydrofuran / 20 °C
View Scheme
参考文献
Gobbi, Silvia; Cavalli, Andrea; Negri, Matthias; Schewe, Katarzyna E.; Belluti, Federica; Piazzi, Lorna; Hartmann, Rolf W.; Recanatini, Maurizio; Bisi, Alessandra
Journal of Medicinal Chemistry, 2007 , vol. 50, # 15 p. 3420 - 3422
反应条件
zinc(II) chloride
T=170 - 180°C;
参考文献
Hanschke
Chemische Berichte, 1899 , vol. 32, p. 2026
