反应条件
1: 85 percent / thionyl chloride, pyridine / diethyl ether / 2 h / 0 °C
2: dimethylsulfoxide / 24 h / 70 - 75 °C
3: NaOMe / methanol / 24 h / 25 °C
4: 80 percent / xylene / 72 h / Heating; 4-Angstroem sieves
5: 100 percent / MCPBA / CH2Cl2 / 30 h / 25 °C
6: 1.) lithium hexamethyldisilazide, 2.) 1 M HCl / 1.) THF, 0 deg C; 25 deg C, 2 h, 2.) 10 min
View Scheme
参考文献
Garver,L.C.; Van Tamelen,E.
Journal of the American Chemical Society, 9182 , vol. 104, p. 867
