3-ethyl-5-(2-hydroxyethyl)-4-methyl-1,3-thiazolium bromide; triethylamine in ethanol T=70 - 80°C; 26.5 h;

1: carbon monoxide With tris-(dibenzylideneacetone)dipalladium(0); triphenylphosphine in tetrahydrofuran T=20°C; P=760.051 Torr; 0.0166667 h; Inert atmosphere; 2: Benzalacetophenone With chloro-trimethyl-silane in tetrahydrofuran T=20°C; 0.166667 h; 3: diethylzinc in tetrahydrofuran T=20°C;

ethanol; 5-(2-hydroxyethyl)-4-methyl-3-(phenylmethyl)thiazolium chloride; triethylamine T=50°C; Stetter reaction; 24 h;

1: KF-18-crown-6 / acetonitrile / 3 h / Heating 2: KMnO4-silica gel / benzene / 2 h / 70 °C View Scheme

2: KMnO4, silica gel / benzene / Heating View Scheme

2: KMnO4, silica gel / benzene / Heating View Scheme