4-(苯并[d][1,3]二氧代l-5-甲基)二氢呋喃-2(3H)-酮合成路线 （共 23 条）
反应条件
jones reagent in water
sonification;
参考文献
Srikrishna; Danieldoss
Synthetic Communications, 2001 , vol. 31, # 15 p. 2357 - 2364
反应条件
1: NaH / tetrahydrofuran
2: lithium aluminum hydride / diethyl ether
3: 81 percent / N-bromosuccinimide / CH2Cl2
4: 80 percent / sodium cyanoborohydride; tri-n-butyltin chloride / AIBN / 2-methyl-propan-2-ol / Heating
5: 71 percent / Jones reagent / H2O / sonification
View Scheme
参考文献
Srikrishna; Danieldoss
Synthetic Communications, 2001 , vol. 31, # 15 p. 2357 - 2364
反应条件
nickel in ethanol
1 h; Ambient temperature;
参考文献
Ishiguro; Mizuguchi; Tomioka; Koga
Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 2 p. 609 - 617
反应条件
sodium acetate; pyridinium chlorochromate
参考文献
Isemori, Yuichi; Kobayashi, Yuichi
Synlett, 2004 , # 11 p. 1941 - 1944
反应条件
1: (iodo-2 trimethoxy-3,4,5 benzyl)-3-butanolide-4, Copper bronze / 0.58 h / 225 °C
2: 69.5 percent / Na / methanol / 1.33 h / Heating
3: 97.5 percent / H2 / 5percent Pd/C / acetic acid / 16 h / 30 °C / 22800 Torr
4: 1.) KOH, 2.) Ca(BH4)2 / 1.) H2O, 2.) ethanol, 10 deg C, 2 h
View Scheme
参考文献
Brown, Eric; Robin, Jean-Pierre; Dhal, Robert
Tetrahedron, 1982 , vol. 38, # 16 p. 2569 - 2580
反应条件
1: 97.5 percent / H2 / 5percent Pd/C / acetic acid / 16 h / 30 °C / 22800 Torr
2: 1.) KOH, 2.) Ca(BH4)2 / 1.) H2O, 2.) ethanol, 10 deg C, 2 h
View Scheme
参考文献
Brown, Eric; Robin, Jean-Pierre; Dhal, Robert
Tetrahedron, 1982 , vol. 38, # 16 p. 2569 - 2580
反应条件
1: 81 percent / N-bromosuccinimide / CH2Cl2
2: 80 percent / sodium cyanoborohydride; tri-n-butyltin chloride / AIBN / 2-methyl-propan-2-ol / Heating
3: 71 percent / Jones reagent / H2O / sonification
View Scheme
参考文献
Srikrishna; Danieldoss
Synthetic Communications, 2001 , vol. 31, # 15 p. 2357 - 2364
反应条件
1: lithium aluminum hydride / diethyl ether
2: 81 percent / N-bromosuccinimide / CH2Cl2
3: 80 percent / sodium cyanoborohydride; tri-n-butyltin chloride / AIBN / 2-methyl-propan-2-ol / Heating
4: 71 percent / Jones reagent / H2O / sonification
View Scheme
参考文献
Srikrishna; Danieldoss
Synthetic Communications, 2001 , vol. 31, # 15 p. 2357 - 2364
反应条件
1: 80 percent / sodium cyanoborohydride; tri-n-butyltin chloride / AIBN / 2-methyl-propan-2-ol / Heating
2: 71 percent / Jones reagent / H2O / sonification
View Scheme
参考文献
Srikrishna; Danieldoss
Synthetic Communications, 2001 , vol. 31, # 15 p. 2357 - 2364
反应条件
1.1: Bu3SnH / Pd(PPh3)4
1.2: NMO; TPAP / 62 h / -78 - 23 °C
1.3: Pd2(dba)3
2.1: 70 percent / H2 / Ra-Ni T4 / 2 h / 75.01 Torr
View Scheme
参考文献
Kamlage; Sefkow; Pool-Zobel; Peter
Chemical Communications, 2001 , # 4 p. 331 - 332
