potassium tert-butylate in diethyl ether; tert-butyl alcohol

1: 88 percent / pyridine / tetrahydrofuran / 0.5 h / 0 °C 2: 81 percent / 1 h / 100 °C 3: 1.) NaH / 1.) THF, 0 deg C, 20 min, 2.) from 0 deg C to room temp., 1 h View Scheme

1: 68 percent / 2 M HCl / methanol / 1 h / Ambient temperature 2: 88 percent / pyridine / tetrahydrofuran / 0.5 h / 0 °C 3: 81 percent / 1 h / 100 °C 4: 1.) NaH / 1.) THF, 0 deg C, 20 min, 2.) from 0 deg C to room temp., 1 h View Scheme

1: 81 percent / 1 h / 100 °C 2: 1.) NaH / 1.) THF, 0 deg C, 20 min, 2.) from 0 deg C to room temp., 1 h View Scheme