4-(1-哌嗪基)苯甲酸乙酯合成路线 （共 13 条）
反应条件
sodium hydroxide in 1,4-dioxane; water T=20°C; 1 h;
参考文献
Kubota, Dai; Ishikawa, Minoru; Yamamoto, Mikio; Murakami, Shoichi; Hachisu, Mitsugu; Katano, Kiyoaki; Ajito, Keiichi
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 7 p. 2089 - 2108
反应条件
1: NaOH / H2O; dioxane / 1 h / 20 °C 2: 400 mg / NaOH / H2O; methanol; tetrahydrofuran / 8 h / 50 °C View Scheme
参考文献
Kubota, Dai; Ishikawa, Minoru; Yamamoto, Mikio; Murakami, Shoichi; Hachisu, Mitsugu; Katano, Kiyoaki; Ajito, Keiichi
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 7 p. 2089 - 2108
反应条件
potassium carbonate in acetonitrile Reflux;
参考文献
CURIS, INC.
Patent: WO2009/36035 A1, 2009 ;
Location in patent: Page/Page column 45 ;
