反应条件
1.1: 82 percent / CuI; Pd(PPh3)2Cl2; Et3N / CH2Cl2 / 6 h / 20 °C
2.1: Br2; Na2SO3 / CH2Cl2; methanol / -78 °C
3.1: 3.49 g / MeONa / methanol; tetrahydrofuran / 3 h / 0 - 20 °C
4.1: NaN[SiMe3]2 / tetrahydrofuran / 1 h / -78 °C
4.2: 86 percent / tetrahydrofuran / -78 - 20 °C
5.1: 90 percent / Pd(PPh3)2Cl2; CuI; Et3N / tetrahydrofuran / 0.5 h / 0 °C
View Scheme
参考文献
Takayama, Yuuki; Hanazawa, Takeshi; Andou, Tomohiro; Muraoka, Kenji; Ohtani, Hiroyuki; Takahashi, Mizuki; Sato, Fumie
Organic Letters, 2004 , vol. 6, # 23 p. 4253 - 4256
