2,3-二氢-6-羟基-3-香豆酮乙酸甲酯合成路线 （共 6 条）
反应条件
hydrogen; palladium 10 on activated carbon in methanol T=20°C; 18 h;
参考文献
WO2008/1931 A2, ;
Page/Page column 88 ;
WO 2008/001931 A2
反应条件
1: sulfuric acid / 4 h / Reflux 2: hydrogen / palladium 10 on activated carbon / methanol / 24 h / 20 °C / 1034.32 Torr View Scheme
参考文献
WO2012/11125 A1, ;
WO 2012/011125 A1
反应条件
1.1: sodium hydroxide; water / 2 h / Reflux 1.2: 20 °C 2.1: sulfuric acid / 4 h / Reflux 3.1: hydrogen / palladium 10 on activated carbon / methanol / 24 h / 20 °C / 1034.32 Torr View Scheme
参考文献
WO2012/11125 A1, ;
WO 2012/011125 A1
反应条件
1.1: sulfuric acid / 2 h / 0 - 20 °C 2.1: sodium hydroxide; water / 2 h / Reflux 2.2: 20 °C 3.1: sulfuric acid / 4 h / Reflux 4.1: hydrogen / palladium 10 on activated carbon / methanol / 24 h / 20 °C / 1034.32 Torr View Scheme
参考文献
WO2012/11125 A1, ;
WO 2012/011125 A1
参考文献
Organic Mass Spectrometry, , vol. 20, # 1 p. 53 - 57
反应条件
CHIRALPAK AD in hexane; isopropyl alcohol Resolution of racemate;
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH
Patent: US2012/302566 A1, 2012 ;
Location in patent: Page/Page column 17-18 ;
