2-[(2-氨基噻唑-4-基)羧基亚甲基氨基氧基]-2-甲基丙酸合成路线 (共 2 条)
反应条件
1.1: dicyclohexyl-carbodiimide / N,N-dimethyl-formamide / 2 h / 30 °C 2.1: methoxybenzene / dichloromethane / 1 h / 0 - 3 °C 3.1: triethylamine / water; methanol / 0 °C / pH 8 - 8.5 3.2: 10 °C / pH 1.3 View Scheme
参考文献
Singh, Janak; Denzel, Theodor W.; Fox, Rita; Kissick, Thomas P.; Herter, Rolf; Wurdinger, Joseph; Schierling, Peter; Papaioannou, Chris G.; Moniot, Jerome L.; Mueller, Richard H.; Cimarusti, Christopher M.
Organic Process Research and Development, 2002 , vol. 6, # 6 p. 863 - 868