3-氨基-4-硝基噻吩-2-羧酸甲酯合成路线 （共 3 条）
反应条件
sodium methylate in methanol
T=55 - 60°C; 1 h;
参考文献
Sauter, Guido; Stulz, Eugen; Leumann, Christian
Helvetica Chimica Acta, 1998 , vol. 81, # 1 p. 14 - 34
反应条件
1: 35 percent / 95percent H2SO4-100percent HNO3 / -25 - 0 °C
2: 80 percent / MeONa / methanol / 1 h / 55 - 60 °C
View Scheme
参考文献
Sauter, Guido; Stulz, Eugen; Leumann, Christian
Helvetica Chimica Acta, 1998 , vol. 81, # 1 p. 14 - 34
反应条件
1: hydrogen
2: pyridine / CHCl3
3: 75 percent / LiAlH4 / tetrahydrofuran / 0 °C
4: 80 percent / pyridinium chlorochromate / CH2Cl2
View Scheme
参考文献
Rossy; Vogel; Hoffman; et al.
Tetrahedron Letters, 1981 , vol. 22, # 36 p. 3493 - 3496
