1-苯基-3-丁烯-1-醇合成路线 （共 285 条）
反应条件
in tetrahydrofuran; dichloromethane; toluene
Inert atmosphere; chemoselective reaction;
参考文献
Oda, Yukiko; Sato, Takaaki; Chida, Noritaka
Organic Letters, 2012 , vol. 14, # 3 p. 950 - 953
反应条件
N,N,N',N',N'',N''-hexamethylphosphoric triamide; n-butyllithium; diisopropylamine in tetrahydrofuran; hexane
-78 deg C, 15 min, allowed to warm to 20 deg C, 2 h at 20 deg C;
参考文献
Eichinger, Peter C. H.; Bowie, John H.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1988 , p. 497 - 506
反应条件
n-butyllithium; zirconocene dichloride
1) THF, hexane, -78 deg C to r.t., 2) THF, hexane, r.t.; Yield given. Multistep reaction;
参考文献
Ito, Hisanaka; Taguchi, Takeo; Hanzawa, Yuji
Tetrahedron Letters, 1992 , vol. 33, # 10 p. 1295 - 1298
反应条件
1: benzaldehyde With titanium tetrachloride
2: methoxybenzene With titanium tetrachloride
T=20°C;
参考文献
Shiina, Isamu; Suzuki, Masahiko; Yokoyama, Kazutoshi
Tetrahedron Letters, 2002 , vol. 43, # 36 p. 6395 - 6398
反应条件
titanium(IV) isopropylate; water; isopropylmagnesium chloride
Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Yamazaki, Takanori; Kasatkin, Aleksandr; Kawanaka, Yasufumi; Sato, Fumie
Journal of Organic Chemistry, 1996 , vol. 61, # 7 p. 2266 - 2267
反应条件
n-butyllithium; sodium hydride
1.) dimethoxyethane, -78 deg C -> r.t., 2.) reflux, 30 min.; Yield given. Multistep reaction;
参考文献
Kabat, Marek M.; Wicha, Jerzy
Tetrahedron Letters, 1991 , vol. 32, # 8 p. 1073 - 1076
反应条件
n-butyllithium
-78 deg C, 0.1 h. Var.: MeLi, 20 deg C, 0.2 h; Yield given. Multistep reaction;
参考文献
Clarembeau, M.; Krief, A.
Tetrahedron Letters, 1984 , vol. 25, # 33 p. 3629 - 3632
反应条件
n-butyllithium
-78 deg C, 0.1 h; Yield given. Multistep reaction;
参考文献
Clarembeau, M.; Krief, A.
Tetrahedron Letters, 1984 , vol. 25, # 33 p. 3629 - 3632
反应条件
bis-(2-hydroxy-ethyl)-amine
1.) RT, 2 h, 2) from 120 deg C to 160 deg C, 2 h; Multistep reaction;
参考文献
Zhou, Weike; Liang, Shaofang; Yu, Su; Luo, Weiming
Journal of Organometallic Chemistry, 1993 , vol. 452, # 1.2 p. 13 - 18
反应条件
hydrogenchloride; titanium tetrachloride
1. CH2Cl2, -78 gradC, 4h; 2. Et2O, room temperature, 6h; Yield given. Multistep reaction;
参考文献
Coppi, Laura; Mordini, Alessandro; Taddei, Maurizio
Tetrahedron Letters, 1987 , vol. 28, # 9 p. 969 - 972
