1-苯基-3-丁烯-1-醇合成路线 （共 285 条）
反应条件
1: N(Et)3 / benzene / Ambient temperature 2: 84 percent / pyridine / benzene / 1 h 3: 74 percent / n-Bu3SnH, AIBN / benzene / Heating View Scheme
参考文献
Bachi, Mario D.; Bosch, Eric
Journal of Organic Chemistry, 1992 , vol. 57, # 17 p. 4696 - 4705
反应条件
2: O3 / CH2Cl2 / -78 °C 3: NaBH4 / methanol View Scheme
参考文献
Master, Hosang E.; Newadkar; Rane; Kumar, Ashok
Tetrahedron Letters, 1996 , vol. 37, # 51 p. 9253 - 9254
反应条件
hydrogen; Lindlar catalyst in methanol P=1034.3 Torr; 2.5 h;
参考文献
Ghosh, Arun K.; Krishnan
Tetrahedron Letters, 1998 , vol. 39, # 9 p. 947 - 948
反应条件
triethylamine; palladium on activated charcoal in toluene T=200°C; 12 h;
参考文献
Journal of Organometallic Chemistry, , vol. 692, # 22 p. 4805 - 4808
反应条件
1: With Zhan 1b catalyst in dichloromethane T=55°C; Olefin cross-metathesis; 24 h; Inert atmosphere; 2: With water; Dess-Martin periodane in dichloromethane T=0°C; Dess-Martin oxidation; 3: With ammonium acetate; acetic acid in ethanol T=55°C; 24 h;
参考文献
Donohoe, Timothy J.; Basutto, Jose A.; Bower, John F.; Rathi, Akshat
Organic Letters, 2011 , vol. 13, # 5 p. 1036 - 1039
反应条件
1: 40 percent / PhSO2Cl, Et3N / CHCl3 / 17 h / Ambient temperature 2: 1) (COCl)2, DMSO, 3) Et3N 3: 48 percent / H2, 42percent aq. HBF3 / Raney Ni / ethanol / 16 h / 760 Torr / Ambient temperature View Scheme
参考文献
Kanemasa Asai; Tanaka
Bulletin of the Chemical Society of Japan, 1991 , vol. 64, # 2 p. 375 - 380
反应条件
1.1: NaH / tetrahydrofuran / 0.5 h / Heating 1.2: 90 percent / tetrahydrofuran / Heating 2.1: 90 percent / [Cl2(PCy3)2Ru=CHPh] / CH2Cl2 / 1 h / 20 °C 3.1: NaOH; 2-propanol; [Cl2(PCy3)2Ru=CHPh] / toluene / 2 h / Heating View Scheme
参考文献
Schmidt, Bernd
Journal of Organic Chemistry, 2004 , vol. 69, # 22 p. 7672 - 7687
反应条件
1.1: amino lipase PS / 70 h / 20 °C / Enzymatic reaction 2.1: sodium hydride / tetrahydrofuran; mineral oil / 1.25 h / 20 °C / Inert atmosphere 2.2: 24 h / Inert atmosphere; Reflux 3.1: sec.-butyllithium / diethyl ether; hexane; cyclohexane / 1 h / -78 °C / Inert atmosphere 3.2: 2 h / -78 °C / Inert atmosphere 4.1: cesium fluoride / dichloromethane; water / 16 h / 20 °C 5.1: tetrahydrofuran / 2 h / 20 °C 6.1: dihydrogen peroxide; sodium hydroxide / water / 0 - 20 °C 7.1: Jone's reagent / acetone / 0 - 20 °C 8.1: chlorosulfonic acid / dichloromethane / 0.75 h / 20 °C View Scheme
参考文献
Roesner, Stefan; Casatejada, Javier Mansilla; Elford, Tim G.; Sonawane, Ravindra P.; Aggarwal, Varinder K.
Organic Letters, 2011 , vol. 13, # 21 p. 5740 - 5743
反应条件
1H-imidazole in N,N-dimethyl-formamide T=20°C;
参考文献
Spangenberg, Thomas; Airiau, Etienne; Thuong, Mathieu Bui The; Donnard, Morgan; Billet, Manuella; Mann, Andre
Synlett, 2008 , # 18 p. 2859 - 2863
反应条件
1: 91 percent / Et3N / diethyl ether / Ambient temperature 2: 1) (COCl)2, DMSO, 3) Et3N 3: 60 percent / H2, 42percent aq. HBF3 / Raney Ni / ethanol / 16 h / 760 Torr / Ambient temperature View Scheme
参考文献
Kanemasa Asai; Tanaka
Bulletin of the Chemical Society of Japan, 1991 , vol. 64, # 2 p. 375 - 380
