1: 83 mg / triethylamine / CH2Cl2 / 0.17 h / 0 °C 2: 65 mg / LiAlH4 / diethyl ether / 0.5 h / Ambient temperature 3: 82 percent / 4-(N,N-dimethylamino)pyridine / pyridine / 10 h / Ambient temperature 4: 1.) CH3COOH, H2O, pyridine, 2.) 4-(N,N-dimethylamino)pyridine / 1.) reflux, 4 h, 2.) RT, 10 h 5: 94 percent / 5percent KOH-MeOH / 1 h / Heating View Scheme

1: 100 percent / LiAlH4 / tetrahydrofuran / 0.5 h / Ambient temperature 2: 83 mg / triethylamine / CH2Cl2 / 0.17 h / 0 °C 3: 65 mg / LiAlH4 / diethyl ether / 0.5 h / Ambient temperature 4: 82 percent / 4-(N,N-dimethylamino)pyridine / pyridine / 10 h / Ambient temperature 5: 1.) CH3COOH, H2O, pyridine, 2.) 4-(N,N-dimethylamino)pyridine / 1.) reflux, 4 h, 2.) RT, 10 h 6: 94 percent / 5percent KOH-MeOH / 1 h / Heating View Scheme

1: 65 mg / LiAlH4 / diethyl ether / 0.5 h / Ambient temperature 2: 82 percent / 4-(N,N-dimethylamino)pyridine / pyridine / 10 h / Ambient temperature 3: 1.) CH3COOH, H2O, pyridine, 2.) 4-(N,N-dimethylamino)pyridine / 1.) reflux, 4 h, 2.) RT, 10 h 4: 94 percent / 5percent KOH-MeOH / 1 h / Heating View Scheme

1: 73 percent / LiBH4, borane-THF / tetrahydrofuran / 12 h / 0 °C 2: 82 percent / 80percent aqu. AcOH / 0.5 h / 50 °C View Scheme

1: 95 percent / MCPBA 2: 73 percent / LiBH4, borane-THF / tetrahydrofuran / 12 h / 0 °C 3: 82 percent / 80percent aqu. AcOH / 0.5 h / 50 °C View Scheme

1: 31 percent / lithium (2-thienyl)cyanocuprate / tetrahydrofuran; petroleum ether / 0.5 h / -78 °C 2: 51 percent / Mg(turnings), MeOH / tetrahydrofuran / 4 h / Ambient temperature 3: 95 percent / MCPBA 4: 73 percent / LiBH4, borane-THF / tetrahydrofuran / 12 h / 0 °C 5: 82 percent / 80percent aqu. AcOH / 0.5 h / 50 °C View Scheme

1: 51 percent / Mg(turnings), MeOH / tetrahydrofuran / 4 h / Ambient temperature 2: 95 percent / MCPBA 3: 73 percent / LiBH4, borane-THF / tetrahydrofuran / 12 h / 0 °C 4: 82 percent / 80percent aqu. AcOH / 0.5 h / 50 °C View Scheme

1: 81 percent / tert-butyl hydroperoxide / 2-methyl-propan-2-ol; CHCl3 / 10 h 2: 31 percent / lithium (2-thienyl)cyanocuprate / tetrahydrofuran; petroleum ether / 0.5 h / -78 °C 3: 51 percent / Mg(turnings), MeOH / tetrahydrofuran / 4 h / Ambient temperature 4: 95 percent / MCPBA 5: 73 percent / LiBH4, borane-THF / tetrahydrofuran / 12 h / 0 °C 6: 82 percent / 80percent aqu. AcOH / 0.5 h / 50 °C View Scheme

1: 66 percent / Et3N / toluene / 48 h / Heating 2: 81 percent / tert-butyl hydroperoxide / 2-methyl-propan-2-ol; CHCl3 / 10 h 3: 31 percent / lithium (2-thienyl)cyanocuprate / tetrahydrofuran; petroleum ether / 0.5 h / -78 °C 4: 51 percent / Mg(turnings), MeOH / tetrahydrofuran / 4 h / Ambient temperature 5: 95 percent / MCPBA 6: 73 percent / LiBH4, borane-THF / tetrahydrofuran / 12 h / 0 °C 7: 82 percent / 80percent aqu. AcOH / 0.5 h / 50 °C View Scheme

1: 85 percent / 70percent t-butyl hydroperoxide, vanadyloxy acetylacetonate / benzene / 2.5 h / Ambient temperature 2: 1.)Et3Al, 2.) 2M HCl / 1.) THF, hexane, 0 deg C, 16 h, 2.) MeOH, THF, room temperature, 1 h 3: 56 percent / toluene-p-sulphonic acid / 17 h / Ambient temperature 4: 65 percent / di-isobitylaluminium hydride / tetrahydrofuran; hexane / 5 h / Ambient temperature 5: 580 mg / pyridine / 16 h / Ambient temperature 6: NaBH4 / methanol; tetrahydrofuran / 3 h / Ambient temperature 7: 260 mg / pyridine / 3 h / Ambient temperature 8: 96 percent / NaI / acetone / 72 h / Heating 9: 98 percent / Bu3SnH / tetrahydrofuran / 18 h / Ambient temperature 10: 396 mg / 5percent KOH-MeOH / tetrahydrofuran / 1 h / Ambient temperature 11: pyridine / 2 h / Ambient temperature 12: 1.) BF3-THF complex, 2.) 2N NaOH, 30percent H2O2, 3.) pyridinium chloroformate 13: 209 mg / LiBr / dimethylformamide / 1 h / Heating 14: 220 mg / OsO4, N-methylmorpholine N-oxide / 2-methyl-propan-2-ol; tetrahydrofuran; H2O / 3 h 15: 70percent AcOH / H2O / 4 h / 65 °C View Scheme