3,5-二甲基-4-碘苯酚合成路线 （共 14 条）
反应条件
hydrogenchloride; KIO3; potassium iodide in methanol
参考文献
Lu, Yixin; Weltrowska, Grazyna; Lemieux, Carole; Chung, Nga N.; Schiller, Peter W.
Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 3 p. 323 - 325
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Lu; Schiller
Synthesis, 2001 , # 11 p. 1639 - 1644
反应条件
tert.-butylhydroperoxide; potassium iodide in methanol; water T=20°C; 8 h;
参考文献
Tetrahedron Letters, , vol. 51, # 16 p. 2170 - 2173
反应条件
dihydrogen peroxide; acetic acid; potassium iodide in water T=20°C; 6 h;
参考文献
Synthetic Communications, , vol. 38, # 22 p. 3894 - 3902
反应条件
iodine in aq. buffer pH=Ca. 9;
参考文献
Russian Journal of Applied Chemistry, , vol. 85, # 9 p. 1355 - 1365
Russ. J. Appl. Chem, , vol. 85, # 9 p. 1355 - 1365,11
反应条件
ammonium hydroxide; iodine; potassium iodide
参考文献
Angewandte Chemie, , vol. 52, p. 263,265
反应条件
n-butyllithium; diethyl ether Behandeln des Reaktionsgemisches mit N-Methyl-formanilid in Aether;
参考文献
Huenig; Schwarz
Justus Liebigs Annalen der Chemie, 1956 , vol. 599, p. 131,132, 139
反应条件
4-(N,N-dimethlyamino)pyridine; triethylamine in tetrahydrofuran; water
参考文献
Lu; Schiller
Synthesis, 2001 , # 11 p. 1639 - 1644
反应条件
1.1: pyridine / 10 °C 1.2: 39 - 55 °C / Large scale reaction 2.1: palladium diacetate; triethylamine; tris-(o-tolyl)phosphine 3.1: [Rh(1,5-COD)(S,S-Et-FerroTANE)]BF4; hydrogen / ethyl acetate / 16 h / 60 °C / 3750.38 Torr 4.1: hydrogenchloride; water / 30 - 90 °C 4.2: 40 - 47 °C / pH 4 View Scheme
参考文献
Praquin, Celine F. B.; De Koning, Pieter D.; Peach, Philip J.; Howard, Roger M.; Spencer, Sarah L.
Organic Process Research and Development, 2011 , vol. 15, # 5 p. 1124 - 1129
反应条件
1: 4-iodo-3,5-dimethyl-phenol With pyridine T=10°C; 2: acetic anhydride T=39 - 55°C; Large scale reaction;
参考文献
Praquin, Celine F. B.; De Koning, Pieter D.; Peach, Philip J.; Howard, Roger M.; Spencer, Sarah L.
Organic Process Research and Development, 2011 , vol. 15, # 5 p. 1124 - 1129
反应条件
1: 1) n-butyllithium / 1) ether, 2 h, reflux, 2) 2 h, reflux
2: 65 percent / charcoal, MgSO4 / benzene / 0.25 h / Heating
View Scheme
参考文献
Koutek, Bohumir; Musil, Lubomir; Velek, Jiri; Lycka, Antonin; Snobl, Dobroslav; et al.
Collection of Czechoslovak Chemical Communications, 1981 , vol. 46, # 10 p. 2540 - 2556
