1,2,3,4-四氢-6-羟基-1-萘羧酸合成路线 （共 32 条）
反应条件
1: lithium hexamethyldisilazane
2: hydrogen; platinum on activated charcoal / methanol
3: methanesulfonic acid; phosphorous pentoxide
4: AlCl3, aluminium chloride / benzene / |Reflux
5: copper(ll) bromide / ethyl acetate; chloroform / |Reflux
6: silver(l) oxide / acetonitrile / 60 °C
7: acetonitrile-D3; water-d2 / |Photolysis
View Scheme
参考文献
Kammath, Viju Balachandran; Solomek, Tomas; Ngoy, Bokolombe Pitchou; Heger, Dominik; Klan, Petr; Rubina, Marina; Givens, Richard S.
Journal of Organic Chemistry, 2013 , vol. 78, # 5 p. 1718 - 1729
反应条件
1: hydrogen; platinum on activated charcoal / methanol
2: methanesulfonic acid; phosphorous pentoxide
3: AlCl3, aluminium chloride / benzene / |Reflux
4: copper(ll) bromide / ethyl acetate; chloroform / |Reflux
5: silver(l) oxide / acetonitrile / 60 °C
6: acetonitrile-D3; water-d2 / |Photolysis
View Scheme
参考文献
Kammath, Viju Balachandran; Solomek, Tomas; Ngoy, Bokolombe Pitchou; Heger, Dominik; Klan, Petr; Rubina, Marina; Givens, Richard S.
Journal of Organic Chemistry, 2013 , vol. 78, # 5 p. 1718 - 1729
反应条件
1: methanesulfonic acid; phosphorous pentoxide
2: AlCl3, aluminium chloride / benzene / |Reflux
3: copper(ll) bromide / ethyl acetate; chloroform / |Reflux
4: silver(l) oxide / acetonitrile / 60 °C
5: acetonitrile-D3; water-d2 / |Photolysis
View Scheme
参考文献
Kammath, Viju Balachandran; Solomek, Tomas; Ngoy, Bokolombe Pitchou; Heger, Dominik; Klan, Petr; Rubina, Marina; Givens, Richard S.
Journal of Organic Chemistry, 2013 , vol. 78, # 5 p. 1718 - 1729
反应条件
1: AlCl3, aluminium chloride / benzene / |Reflux
2: copper(ll) bromide / ethyl acetate; chloroform / |Reflux
3: silver(l) oxide / acetonitrile / 60 °C
4: acetonitrile-D3; water-d2 / |Photolysis
View Scheme
参考文献
Kammath, Viju Balachandran; Solomek, Tomas; Ngoy, Bokolombe Pitchou; Heger, Dominik; Klan, Petr; Rubina, Marina; Givens, Richard S.
Journal of Organic Chemistry, 2013 , vol. 78, # 5 p. 1718 - 1729
反应条件
1: silver(l) oxide / acetonitrile / 60 °C
2: acetonitrile-D3; water-d2 / |Photolysis
3: potassium carbonate / acetonitrile / 20 °C
4: potassium permanganate / benzene / |Reflux; |Dean-Stark
5: palladium 10 on activated carbon; hydrogen / ethyl acetate / 20 °C
6: acetonitrile-D3; water-d2 / |Photolysis
View Scheme
参考文献
Kammath, Viju Balachandran; Solomek, Tomas; Ngoy, Bokolombe Pitchou; Heger, Dominik; Klan, Petr; Rubina, Marina; Givens, Richard S.
Journal of Organic Chemistry, 2013 , vol. 78, # 5 p. 1718 - 1729
反应条件
1: acetonitrile-D3; water-d2 / |Photolysis
2: potassium carbonate / acetonitrile / 20 °C
3: potassium permanganate / benzene / |Reflux; |Dean-Stark
4: palladium 10 on activated carbon; hydrogen / ethyl acetate / 20 °C
5: acetonitrile-D3; water-d2 / |Photolysis
View Scheme
参考文献
Kammath, Viju Balachandran; Solomek, Tomas; Ngoy, Bokolombe Pitchou; Heger, Dominik; Klan, Petr; Rubina, Marina; Givens, Richard S.
Journal of Organic Chemistry, 2013 , vol. 78, # 5 p. 1718 - 1729
反应条件
1: palladium 10 on activated carbon; hydrogen / ethyl acetate / 20 °C
2: acetonitrile-D3; water-d2 / |Photolysis
View Scheme
参考文献
Kammath, Viju Balachandran; Solomek, Tomas; Ngoy, Bokolombe Pitchou; Heger, Dominik; Klan, Petr; Rubina, Marina; Givens, Richard S.
Journal of Organic Chemistry, 2013 , vol. 78, # 5 p. 1718 - 1729
反应条件
1: silver(l) oxide / acetonitrile / 60 °C
2: acetonitrile-D3; water-d2 / |Photolysis
3: potassium carbonate / acetonitrile / 20 °C
4: potassium permanganate / benzene / |Reflux; |Dean-Stark
5: palladium 10 on activated carbon; hydrogen / ethyl acetate / 20 °C
6: acetonitrile-D3; water-d2 / |Photolysis
View Scheme
参考文献
Kammath, Viju Balachandran; Solomek, Tomas; Ngoy, Bokolombe Pitchou; Heger, Dominik; Klan, Petr; Rubina, Marina; Givens, Richard S.
Journal of Organic Chemistry, 2013 , vol. 78, # 5 p. 1718 - 1729
反应条件
1: silver(l) oxide / acetonitrile / 60 °C
2: acetonitrile-D3; water-d2 / |Photolysis
View Scheme
参考文献
Kammath, Viju Balachandran; Solomek, Tomas; Ngoy, Bokolombe Pitchou; Heger, Dominik; Klan, Petr; Rubina, Marina; Givens, Richard S.
Journal of Organic Chemistry, 2013 , vol. 78, # 5 p. 1718 - 1729
反应条件
1: acetonitrile-D3; water-d2 / |Photolysis
2: potassium carbonate / acetonitrile / 20 °C
3: potassium permanganate / benzene / |Reflux; |Dean-Stark
4: palladium 10 on activated carbon; hydrogen / ethyl acetate / 20 °C
5: acetonitrile-D3; water-d2 / |Photolysis
View Scheme
参考文献
Kammath, Viju Balachandran; Solomek, Tomas; Ngoy, Bokolombe Pitchou; Heger, Dominik; Klan, Petr; Rubina, Marina; Givens, Richard S.
Journal of Organic Chemistry, 2013 , vol. 78, # 5 p. 1718 - 1729
