(±)-α-甲氧基-α-(三氟甲基)苯乙腈合成路线 （共 11 条）
参考文献
Aareskjold, Kare; Liaaen-Jensen, Synnove
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1982 , vol. 36, # 8 p. 499 - 504
反应条件
1: 1.) magnesium / 1.) ether, 1.5 h, 2.) ether, 12 h; reflux, 1.5 h 2: 1,) 1,2-dimethoxyethane, 1.5 h, 2.) 50 deg C View Scheme
参考文献
Bulletin des Societes Chimiques Belges, , vol. 95, # 7 p. 547 - 556
反应条件
1: 35 percent aq. H2O2, NaOH / ethanol; H2O / 1.) 1 h, 0 deg C, 2.) 2 h, reflux 2: NaOH / H2O / 5 h / Heating View Scheme
参考文献
Hull, William E.; Seeholzer, Klaus; Baumeister, Marlies; Ugi, Ivar
Tetrahedron, 1986 , vol. 42, # 2 p. 547 - 552
反应条件
hydrolysis; Yield given. Yields of byproduct given;
参考文献
Aareskjold, Kare; Liaaen-Jensen, Synnove
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1982 , vol. 36, # 8 p. 499 - 504
反应条件
1: 61 percent / hydrolysis 2: 20 g / SOCl2 View Scheme
参考文献
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, , vol. 36, # 8 p. 499 - 504
反应条件
1: 35 percent aq. H2O2, NaOH / ethanol; H2O / 1.) 1 h, 0 deg C, 2.) 2 h, reflux 2: NaOH / H2O / 5 h / Heating View Scheme
参考文献
Hull, William E.; Seeholzer, Klaus; Baumeister, Marlies; Ugi, Ivar
Tetrahedron, 1986 , vol. 42, # 2 p. 547 - 552
反应条件
hydrolysis; Yield given. Yields of byproduct given;
参考文献
Aareskjold, Kare; Liaaen-Jensen, Synnove
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1982 , vol. 36, # 8 p. 499 - 504
反应条件
1: 35 percent aq. H2O2, NaOH / ethanol; H2O / 1.) 1 h, 0 deg C, 2.) 2 h, reflux 2: NaOH / H2O / 5 h / Heating View Scheme
参考文献
Hull, William E.; Seeholzer, Klaus; Baumeister, Marlies; Ugi, Ivar
Tetrahedron, 1986 , vol. 42, # 2 p. 547 - 552
反应条件
hydrolysis; Yield given. Yields of byproduct given;
参考文献
Aareskjold, Kare; Liaaen-Jensen, Synnove
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1982 , vol. 36, # 8 p. 499 - 504
反应条件
1: 35 percent aq. H2O2, NaOH / ethanol; H2O / 1.) 1 h, 0 deg C, 2.) 2 h, reflux 2: NaOH / H2O / 5 h / Heating View Scheme
参考文献
Hull, William E.; Seeholzer, Klaus; Baumeister, Marlies; Ugi, Ivar
Tetrahedron, 1986 , vol. 42, # 2 p. 547 - 552
