3-苯并[1,3]二氧杂环戊烯-5-异噁唑-5-甲醛合成路线 （共 3 条）
反应条件
silica gel; pyridinium chlorochromate in dichloromethane
5 h;
参考文献
Jung, Hee Kyung; Doddareddy, Munikumar Reddy; Cha, Joo Hwan; Rhim, Hyewhon; Cho, Yong Seo; Koh, Hun Yeong; Jung, Bong Young; Pae, Ae Nim
Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 15 p. 3965 - 3970
反应条件
1.1: N-chlorosuccinimide; pyridine / tetrahydrofuran / 0.5 h / 60 °C
1.2: triethylamine / tetrahydrofuran / 2 h / 50 °C
2.1: pyridinium chlorochromate; silica gel / CH2Cl2 / 5 h
View Scheme
参考文献
Jung, Hee Kyung; Doddareddy, Munikumar Reddy; Cha, Joo Hwan; Rhim, Hyewhon; Cho, Yong Seo; Koh, Hun Yeong; Jung, Bong Young; Pae, Ae Nim
Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 15 p. 3965 - 3970
反应条件
1.1: NH2OH*HCl; Na2CO3 / ethanol; H2O / 1 h / 60 °C
2.1: N-chlorosuccinimide; pyridine / tetrahydrofuran / 0.5 h / 60 °C
2.2: triethylamine / tetrahydrofuran / 2 h / 50 °C
3.1: pyridinium chlorochromate; silica gel / CH2Cl2 / 5 h
View Scheme
参考文献
Jung, Hee Kyung; Doddareddy, Munikumar Reddy; Cha, Joo Hwan; Rhim, Hyewhon; Cho, Yong Seo; Koh, Hun Yeong; Jung, Bong Young; Pae, Ae Nim
Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 15 p. 3965 - 3970
