7-溴咪唑并[1,2-a]吡啶合成路线 （共 3 条）
反应条件
in ethanol; water T=20°C; 12 h; Heating / reflux;
参考文献
ARRAY BIOPHARMA INC.
Patent: WO2008/124323 A1, 2008 ;
Location in patent: Page/Page column 68 ;
WO 2008/124323 A1
反应条件
iodine; sodium acetate in methanol T=0°C;
参考文献
WO2010/108074 A2, ;
Page/Page column 63 ;
WO 2010/108074 A2
反应条件
dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct; potassium acetate in 1,4-dioxane
T=90°C; 18 h; Sealed tubeInert atmosphereMicrowave irradiation;
参考文献
GLAXOSMITHKLINE LLC; ADAMS, Nicholas, David; CHAUDHARI, Amita, M.; KIESOW, Terence, John; McSHERRY, Allison, K.; MOORE, Michael, Lee; PARRISH, Cynthia, Ann; REIF, Alexander, Joseph; RIDGERS, Lance, Howard
Patent: WO2014/8223 A2, 2014 ;
Location in patent: Page/Page column 58-59 ;
