6-氯-4-甲氧基-3-吡嗪胺合成路线 （共 3 条）
反应条件
sodium methylate
T=0 - 20°C; Inert atmosphere;
参考文献
F. HOFFMANN-LA ROCHE AG; HOFFMANN-LA ROCHE INC.; FLOHR, Alexander; GROEBKE ZBINDEN, Katrin; LERNER, Christian
Patent: WO2014/72261 A1, 2014 ;
Location in patent: Page/Page column 40 ;
反应条件
sodium methylate in methanol
16 h;
参考文献
ASTRAZENECA AB
Patent: WO2004/108690 A1, 2004 ;
Location in patent: Page/Page column 15 ;
WO 2004/108690 A1
参考文献
ASTELLAS PHARMA INC.
Patent: WO2007/13673 A1, 2007 ;
Location in patent: Page/Page column 41-42 ;
WO 2007/013673 A1
