1.1: aq. NaOH / 1 h / 20 °C
1.2: cetyl trimethylammonium bromide / toluene / Heating
2.1: NaOEt; EtOH / 0.5 h / 55 °C
2.2: aq. HCl / 0.5 h / 20 °C
View Scheme
参考文献
Brooke, Edward W.; Davies, Stephen G.; Mulvaney, Andrew W.; Okada, Minoru; Pompeo, Frederique; Sim, Edith; Vickers, Richard J.; Westwood, Isaac M.
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 15 p. 2527 - 2530