ELI LILLY AND COMPANY; BLANCO-PILLADO, Maria-Jesus; VETMAN, Tatiana Natali; FISHER, Matthew Joseph; KUKLISH, Steven Lee
Patent: WO2014/4230 A1, 2014 ;
Location in patent: Page/Page column 16; 17 ;
1: potassium permanganate; sodium hydroxide / water / 12 h / |Reflux
2: sulfuric acid / methanol / |Reflux
3: palladium 10 on activated carbon; hydrogen / ethyl acetate / 20 h / 20 °C
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参考文献
Meiries, Sebastien; Le Duc, Gaetan; Chartoire, Anthony; Collado, Alba; Speck, Klaus; Arachchige, Kasun S. Athukorala; Slawin, Alexandra M. Z.; Nolan, Steven P.
Chemistry - A European Journal, 2013 , vol. 19, # 51 p. 17358 - 17368