1,4,5,8-四羟基蒽醌合成路线 （共 20 条）
反应条件
1: With sodium hydroxide; water 3 h; Heating / reflux; 2: With sodium hydrogensulfite in water 3 h; Heating / reflux; 3: With hydrogenchloride in water pH=3;
参考文献
SCHOOL OF PHARMACY, UNIVERSITY OF LONDON
Patent: WO2005/61453 A1, 2005 ;
Location in patent: Page/Page column 19 ;
反应条件
sodium hydroxide; sodium dithionite T=100°C; 1 h;
参考文献
Johnson, Mary G.; Kiyokawa, Hiroshi; Tani, Shohei; Koyama, Junko; Morris-Natschke, Susan L.; Mauger, Anthony; Bowers-Daines, Margaret M.; Lange, Barry C.; Lee, Kuo-Hsiung
Bioorganic and Medicinal Chemistry, 1997 , vol. 5, # 8 p. 1469 - 1479
反应条件
water; trifluoroacetic acid T=65°C; 1 h;
参考文献
Harrison, Charles R.; Hodge, Philip; Khan, Naeem
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 1592 - 1594
反应条件
nitrobenzene 0.25 h; Heating;
参考文献
Norvez, Sophie
Journal of Organic Chemistry, 1993 , vol. 58, # 9 p. 2414 - 2418
反应条件
sodium dithionite in water T=100°C; 0.666667 h;
参考文献
J. Appl. Chem. USSR (Engl. Transl.), , vol. 60, # 10 p. 2326 - 2330,2151 - 2153
反应条件
sodium dithionite in water T=100°C; 0.666667 h;
参考文献
J. Appl. Chem. USSR (Engl. Transl.), , vol. 60, # 10 p. 2326 - 2330,2151 - 2153
反应条件
hydrogenchloride T=180°C;
参考文献
Chemische Berichte, , vol. 61, p. 988
反应条件
1: 88 percent / sodium dithionite / H2O / 0.67 h / 100 °C 2: nitrobenzene / Heating View Scheme
参考文献
J. Appl. Chem. USSR (Engl. Transl.), , vol. 60, # 10 p. 2326 - 2330,2151 - 2153
反应条件
aluminium trichloride; sodium chloride
参考文献
Journal of Organic Chemistry, , vol. 6, p. 732,747
Journal of Organic Chemistry, , vol. 7, p. 63,66
反应条件
1: 76 percent / boric acid, nitric acid, oleum / 25 °C 2: 100 percent / sulfuric acid, iron / 0.5 h / 90 °C 3: 1.) 10percent aq. NaOH, 2.) sodium hydrosulfite / 1.) n-BuOH, 15 min, 2.) n-BuOH, 60 deg C, 30 min View Scheme
参考文献
Synthetic Communications, , vol. 25, # 13 p. 1893 - 1900
