1.1: nitric acid; bromine / 4.17 h / 50 °C
2.1: sodium hydroxide / 0.25 h / 50 °C
2.2: 48 h / 50 °C / |Reflux
3.1: 1-methyl-pyrrolidin-2-one / 48 h / 130 °C / |Inert atmosphere
View Scheme
参考文献
Moseley, Jonathan D.; Moss, William O.; Welham, Matthew J.; Ancell, Claire L.; Banister, John; Bowden, Sharon A.; Norton, Glenn; Young, Maureen J.
Organic Process Research and Development, 2003 , vol. 7, # 1 p. 58 - 66
1: 30 percent / sodium acetate / 2 h / 240 °C
2: 57 percent / SO2Cl2 / diethyl ether / 1 h / Heating
View Scheme
参考文献
Ayyangar, N. R.; Joshi, S. V.; Lugade, A. G.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1981 , vol. 20, # 12 p. 1043 - 1046
