trimethylsilyl trifluoromethanesulfonate; N-ethyl-N,N-diisopropylamine in dichloromethane T=20°C; 6 h;

pyridine; chromium(VI) oxide in dichloromethane 1 h; Heating;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '11604118', constants.ctx, '0')">tetrakis(triphenylphosphine) palladium⁽⁰⁾</a> <br />&nbsp;1.) THF, 0 deg C then RT; 2.) 16-24 h, 65 deg C;&nbsp;&nbsp;Yield given. Multistep reaction;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: 82 percent / N-bromosuccinimide / CH₂Cl₂ / 1.) -20 deg C, 2 h, 2.) 15 deg C<br />2: 73 percent / 10 N aq. NaOH, NaBH₄, chlorocobaloxime(III) / ethanol / 0.5 h / 50 - 60 &deg;C<br /> <br /> &nbsp;