4-羟基-6-十一烷基-2H-吡喃-2-酮合成路线 （共 8 条）
反应条件
type III polyketide synthase RppA from S. griseus; 2-hydroxyethanethiol in various solvent(s)
T=37°C; pH=7.5; 2 h;
参考文献
Jeong, Jae-Cheol; Srinivasan, Aravind; Grueschow, Sabine; Bach, Horacio; Sherman, David H.; Dordick, Jonathan S.
Journal of the American Chemical Society, 2005 , vol. 127, # 1 p. 64 - 65
反应条件
sulfuric acid
T=130°C; 0.25 h;
参考文献
Cook; Ternai; Ghosh
Journal of Medicinal Chemistry, 1987 , vol. 30, # 6 p. 1017 - 1023
反应条件
sulfuric acid
T=130°C; 0.3 h;
参考文献
Bacardit, Ramon; Moreno-Manas, Marcial
Chemistry Letters, 1982 , p. 5 - 6
反应条件
n-butyllithium
Multistep reaction;
参考文献
Groutas, William C.; Stanga, Michael A.; Brubaker, Michael J.; Huang, Tien L.; Moi, Min K.; Carroll, Robert T.
Journal of Medicinal Chemistry, 1985 , vol. 28, # 8 p. 1106 - 1109
反应条件
alkylresorcylic acid synthase, ARAS2
T=30°C; pH=7; 0.333333 h; aq. phosphate bufferEnzymatic reaction;
参考文献
Matsuzawa, Miku; Katsuyama, Yohei; Funa, Nobutaka; Horinouchi, Sueharu
Phytochemistry, 2010 , vol. 71, # 10 p. 1059 - 1067
反应条件
ethylenediaminetetraacetic acid; recombinant Arachis hypogaea stilbene synthase in various solvent(s)
T=30°C; pH=8.0; 0.333333 h; Enzyme kinetics;
参考文献
Abe, Ikuro; Watanabe, Tatsuya; Noguchi, Hiroshi
Phytochemistry, 2004 , vol. 65, # 17 p. 2447 - 2453
反应条件
Botrytis cinerea type III polyketide synthase
Enzymatic reaction; Kinetics;
参考文献
Jeya, Marimuthu; Kim, Tae-Su; Tiwari, Manish Kumar; Li, Jinglin; Lee, Jung-Kul; Zhao, Huimin
Molecular BioSystems, 2012 , vol. 8, # 11 p. 2864 - 2867,4
反应条件
1: H2 / Ra-Ni / ethanol / 760 Torr / Ambient temperature
2: TsOH / benzene / Heating
3: H2 / Pd-Ac(10percent) / ethyl acetate / 760 Torr / Ambient temperature
View Scheme
参考文献
Bacardit, Ramon; Moreno-Manas, Marcial
Chemistry Letters, 1982 , p. 5 - 6
