反应条件
1: 1.) N-bromosuccinimide, water, 2.) 1N NaOH / 1.) ether, 5 d, 20 deg C, 2.) water, 4h, 20 deg C
2: methanol / 48 h / Heating
3: 27 percent / 1N hydrochloric acid / H2O / 1.) 24 h, 20 deg C, 2.) 3 h, 80 deg C
View Scheme
参考文献
Urbain; Schumer; Gubin; Descamps
European Journal of Medicinal Chemistry, 1982 , vol. 17, # 4 p. 359 - 364
