反应条件
1: 60 percent / NaOH / methanol / a) 24h b) H2O, 0 deg C, HCl
2: 90 percent / hexamethylphosphoric acid triamide / 3 h / 180 °C
3: 90 percent / LiAlH4 / diethyl ether / a. reflux while adding reagent b. overnight room temperature c. reflux, 3h
4: 70 percent / pyridinium chlorochromate, NaOAc / CH2Cl2 / 3 h / Ambient temperature
5: 70 percent / Mg / tetrahydrofuran / a. ice-cooled solution, 10 min b. overnight room temperature c. 3h reflux
6: 50 percent / mercuric acetate / 16 h / Heating
7: 80 percent / 0.58 h / 180 °C / sealed tube
8: 90 percent / LiAlH4 / diethyl ether / a. reflux while adding reagent b. overnight room temperature c. 1h reflux
9: Et3N / CH2Cl2 / 0 °C
10: 1.) cuprous iodide / 1.) Et2O, -10 deg C, 1o min 2. 4h, 0 deg C
11: 80 percent / PTS / methanol / 4 h
View Scheme
参考文献
Vig, O. P.; Sharma, M. L.; Verma, N. K.; Malik, Neera
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1981 , vol. 20, # 10 p. 860 - 862
