1-溴-2,3,5-三氯苯合成路线 （共 4 条）
反应条件
sodium nitrite; Copper(I)chloride in hydrogenchloride; chloroform; sulfuric acid; acetic acid
反应条件
(R,R)-N,N'-bis[(2-fluorophenyl)methyl]-1,2-cyclohexanediamine PdCl2 complex; potassium carbonate in N,N-dimethyl-formamide T=120°C; Suzuki coupling; 24 h; Aerobic conditions;
参考文献
Kylmaelae, Tuula; Kuuloja, Noora; Xu, Youjun; Rissanen, Kari; Franzen, Robert
European Journal of Organic Chemistry, 2008 , # 23 p. 4019 - 4024
反应条件
(R,R)-N,N'-bis[(2-fluorophenyl)methyl]-1,2-cyclohexanediamine PdCl2 complex; potassium carbonate in N,N-dimethyl-formamide T=120°C; Suzuki coupling; 24 h; Aerobic conditions;
参考文献
Kylmaelae, Tuula; Kuuloja, Noora; Xu, Youjun; Rissanen, Kari; Franzen, Robert
European Journal of Organic Chemistry, 2008 , # 23 p. 4019 - 4024
反应条件
magnesium in hydrogenchloride
参考文献
Glaxo Wellcome, Inc.
Patent: US6255307 B1, 2001 ;
