3-[2-(二甲基氨基)乙氧基]苯甲醛合成路线 （共 4 条）
反应条件
sodium methylate in chlorobenzene
15 h; Heating;
参考文献
Bartl; Holubek; Svatek; et al.
Collection of Czechoslovak Chemical Communications, 1983 , vol. 48, # 4 p. 1173 - 1186
反应条件
1: meta-hydroxybenzaldehyde With di-isopropyl azodicarboxylate; triphenylphosphine in tetrahydrofuran
T=20°C; 0.25 h;
2: 2-(dimethylamino)-ethanol in tetrahydrofuran
T=20°C; 24 h;
参考文献
CEPHALON, INC.; BRESLIN, Henry J.; CURRY, Matthew A.; GINGRICH, Diane E.; LEARN, Keith S.; OTT, Gregory R.; WAGNER, Jason C.
Patent: WO2013/116291 A1, 2013 ;
Location in patent: Page/Page column 231 ;
反应条件
caesium carbonate in N,N-dimethyl-formamide
T=50°C; 18 h;
参考文献
Patt, William C.; Cheng, Xue-Min; Repine, Joseph T.; Lee, Chet; Reisdorph, Bill R.; Massa, Mark A.; Doherty, Annette M.; Welch, Kathleen M.; Bryant, John W.; Flynn, Michael A.; Walker, Donnelle M.; Schroeder, Richard L.; Haleen, Stephen J.; Keiser, Joan A.
Journal of Medicinal Chemistry, 1999 , vol. 42, # 12 p. 2162 - 2168
反应条件
in methanol; water
T=20°C; 60 h;
参考文献
Nagarapu, Lingaiah; Aneesa; Satyender, Apuri; Chandana; Bantu, Rajaskaker
Journal of Heterocyclic Chemistry, 2009 , vol. 46, # 2 p. 195 - 200
