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结构式
乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
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乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
81100-62-1
合成路线
（共 8 条）
3641-08-5
2H-1,2,4-三氮唑-3-甲酰胺
+
81100-62-1
→
反应条件
578-76-7
7-甲基鸟嘌呤
+
36791-04-5
利巴韦林
反应条件
phosphate buffer; purine nucleoside phosphorylase in water T=25°C; 48 h; pH 7.4;
参考文献
Hennen; Wong
Journal of Organic Chemistry, 1989 , vol. 54, # 19 p. 4692 - 4695
81100-62-1
+
10310-21-1
2-氨基-6-氯嘌呤
→
反应条件
2004-07-1
6-氯鸟嘌呤核苷
+
578-76-7
7-甲基鸟嘌呤
反应条件
recombinant purine nucleoside phosphorylase from Aeromonas hydrophila T=20°C; pH=7.5; aq. phosphate bufferEnzymatic reaction; regioselective reaction;
参考文献
Ubiali, Daniela; Serra, Carla D.; Serra, Immacolata; Morelli, Carlo F.; Terreni, Marco; Albertini, Alessandra M.; Manitto, Paolo; Speranzab, Giovanna
Advanced Synthesis and Catalysis, 2012 , vol. 354, # 1 p. 96 - 104
81100-62-1
+
1198-47-6
2-氨基-6-巯嘌呤
→
反应条件
578-76-7
7-甲基鸟嘌呤
+
4914-73-2
反应条件
recombinant purine nucleoside phosphorylase from Aeromonas hydrophila T=20°C; pH=7.5; aq. phosphate bufferEnzymatic reaction; regioselective reaction;
参考文献
Ubiali, Daniela; Serra, Carla D.; Serra, Immacolata; Morelli, Carlo F.; Terreni, Marco; Albertini, Alessandra M.; Manitto, Paolo; Speranzab, Giovanna
Advanced Synthesis and Catalysis, 2012 , vol. 354, # 1 p. 96 - 104
81100-62-1
+
1074-89-1
6-氯嘌呤
→
反应条件
578-76-7
7-甲基鸟嘌呤
+
5746-29-2
6-O-甲基肌苷
反应条件
recombinant purine nucleoside phosphorylase from Aeromonas hydrophila T=20°C; pH=7.5; aq. phosphate bufferEnzymatic reaction; regioselective reaction;
参考文献
Ubiali, Daniela; Serra, Carla D.; Serra, Immacolata; Morelli, Carlo F.; Terreni, Marco; Albertini, Alessandra M.; Manitto, Paolo; Speranzab, Giovanna
Advanced Synthesis and Catalysis, 2012 , vol. 354, # 1 p. 96 - 104
81100-62-1
+
2004-03-7
6-甲基嘌呤
→
反应条件
578-76-7
7-甲基鸟嘌呤
+
14675-48-0
(2R,3s,4r,5r)-2-(羟基甲基)-5-(6-甲基-9h-嘌呤-9-基)四氢呋喃-3,4-二醇
反应条件
recombinant purine nucleoside phosphorylase from Aeromonas hydrophila in glycerol T=20°C; pH=7.5; aq. phosphate bufferEnzymatic reaction; regioselective reaction;
参考文献
Ubiali, Daniela; Serra, Carla D.; Serra, Immacolata; Morelli, Carlo F.; Terreni, Marco; Albertini, Alessandra M.; Manitto, Paolo; Speranzab, Giovanna
Advanced Synthesis and Catalysis, 2012 , vol. 354, # 1 p. 96 - 104
4261-05-6
+
81100-62-1
→
反应条件
6736-58-9
4-氨基-1-BETA-D-呋喃核糖基-1H-咪唑并[4,5-C]吡啶
+
578-76-7
7-甲基鸟嘌呤
反应条件
purine nucleoside phosphorylase in water T=25°C; 48 h; pH 7.0-7.4;
参考文献
Hennen; Wong
Journal of Organic Chemistry, 1989 , vol. 54, # 19 p. 4692 - 4695
81100-62-1
+
10310-21-1
2-氨基-6-氯嘌呤
→
反应条件
2004-07-1
6-氯鸟嘌呤核苷
+
578-76-7
7-甲基鸟嘌呤
反应条件
recombinant purine nucleoside phosphorylase from Aeromonas hydrophila T=20°C; pH=7.5; aq. phosphate bufferEnzymatic reaction; regioselective reaction;
参考文献
Ubiali, Daniela; Serra, Carla D.; Serra, Immacolata; Morelli, Carlo F.; Terreni, Marco; Albertini, Alessandra M.; Manitto, Paolo; Speranzab, Giovanna
Advanced Synthesis and Catalysis, 2012 , vol. 354, # 1 p. 96 - 104
81100-62-1
+
2004-03-7
6-甲基嘌呤
→
反应条件
578-76-7
7-甲基鸟嘌呤
+
14675-48-0
(2R,3s,4r,5r)-2-(羟基甲基)-5-(6-甲基-9h-嘌呤-9-基)四氢呋喃-3,4-二醇
反应条件
recombinant purine nucleoside phosphorylase from Aeromonas hydrophila in glycerol T=20°C; pH=7.5; aq. phosphate bufferEnzymatic reaction; regioselective reaction;
参考文献
Ubiali, Daniela; Serra, Carla D.; Serra, Immacolata; Morelli, Carlo F.; Terreni, Marco; Albertini, Alessandra M.; Manitto, Paolo; Speranzab, Giovanna
Advanced Synthesis and Catalysis, 2012 , vol. 354, # 1 p. 96 - 104
