1: 6-O-methylerythromycin A N-oxide With sodium hydrogensulfite in ethanol; water T=20°C; 1 h; 2: With sodium carbonate in ethanol; water 3: formaldehyd With formic acid; sodium carbonate more than 3 stages;
1: With formic acid in ethanol; water T=40 - 45°C; pH=2.5 - 3.5; 3 h; 2: With sodium hydrogensulfite in ethanol; water 1 h; Heating / reflux; Product distribution / selectivity;
1: With formic acid; sodium hydrogensulfite in denatured spirit 2 h; Heating / reflux; 2: With sodium hydroxide in denatured spirit; water T=20°C; pH=10.5; Product distribution / selectivity;
1: With Na2S2O5; formic acid; water in ethanol T=25 - 63°C; pH=3.8 - 4.1; 10 h; 2: With sodium hydroxide in ethanol; water T=30 - 35°C; pH=10.5 - 11.0; 0.5 h; Product distribution / selectivity;
