9-羟基-10-甲基-3-(3-甲基-2-丁烯基)-1,2,3,4,4a,5,6,10b-八氢苯并(f)异喹啉合成路线 （共 5 条）
反应条件
sodium hydrogencarbonate in N,N-dimethyl-formamide
4 h; Heating;
参考文献
Dammertz; Reimann
Archiv der Pharmazie, 1982 , vol. 315, # 1 p. 27 - 32
反应条件
1: 97 percent / acetone / 15 h / Ambient temperature
2: aq. NaOH, NaBH4 / methanol / 0.5 h
3: 71 percent / 48percent HBr / acetic acid / 12 h / Heating
4: H2, aq. HCl / 10percent Pd/C / ethanol / 96 h / Ambient temperature
5: 55 percent / NaHCO3 / dimethylformamide / 4 h / Heating
View Scheme
参考文献
Dammertz; Reimann
Archiv der Pharmazie, 1982 , vol. 315, # 1 p. 27 - 32
反应条件
1: 71 percent / 48percent HBr / acetic acid / 12 h / Heating
2: H2, aq. HCl / 10percent Pd/C / ethanol / 96 h / Ambient temperature
3: 55 percent / NaHCO3 / dimethylformamide / 4 h / Heating
View Scheme
参考文献
Dammertz; Reimann
Archiv der Pharmazie, 1982 , vol. 315, # 1 p. 27 - 32
反应条件
1: aq. NaOH, NaBH4 / methanol / 0.5 h
2: 71 percent / 48percent HBr / acetic acid / 12 h / Heating
3: H2, aq. HCl / 10percent Pd/C / ethanol / 96 h / Ambient temperature
4: 55 percent / NaHCO3 / dimethylformamide / 4 h / Heating
View Scheme
参考文献
Dammertz; Reimann
Archiv der Pharmazie, 1982 , vol. 315, # 1 p. 27 - 32
反应条件
1: H2, aq. HCl / 10percent Pd/C / ethanol / 96 h / Ambient temperature
2: 55 percent / NaHCO3 / dimethylformamide / 4 h / Heating
View Scheme
参考文献
Dammertz; Reimann
Archiv der Pharmazie, 1982 , vol. 315, # 1 p. 27 - 32
