5-溴-2-(1H-吡唑-3-基)吡啶合成路线 （共 5 条）
反应条件
hydrazine hydrate in ethanol
1 h; Heating;
参考文献
Jo, Yeong Woo; Im, Weon Bin; Rhee, Jae Keol; Shim, Mi Ja; Kim, Won Bae; Choi, Eung Chil
Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 22 p. 5909 - 5915
反应条件
1: 65 percent / NaCN / dimethylformamide / 3 h / Heating
2: tetrahydrofuran / 2 h / -20 °C
3: 15 h / Heating
4: 71 percent / hydrazine hydrate / ethanol / 1 h / Heating
View Scheme
参考文献
Jo, Yeong Woo; Im, Weon Bin; Rhee, Jae Keol; Shim, Mi Ja; Kim, Won Bae; Choi, Eung Chil
Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 22 p. 5909 - 5915
反应条件
1: tetrahydrofuran / 2 h / -20 °C
2: 15 h / Heating
3: 71 percent / hydrazine hydrate / ethanol / 1 h / Heating
View Scheme
参考文献
Jo, Yeong Woo; Im, Weon Bin; Rhee, Jae Keol; Shim, Mi Ja; Kim, Won Bae; Choi, Eung Chil
Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 22 p. 5909 - 5915
反应条件
1: 15 h / Heating
2: 71 percent / hydrazine hydrate / ethanol / 1 h / Heating
View Scheme
参考文献
Jo, Yeong Woo; Im, Weon Bin; Rhee, Jae Keol; Shim, Mi Ja; Kim, Won Bae; Choi, Eung Chil
Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 22 p. 5909 - 5915
反应条件
potassium hydroxide in N,N-dimethyl-formamide
T=0°C; 1 h;
参考文献
Jo, Yeong Woo; Im, Weon Bin; Rhee, Jae Keol; Shim, Mi Ja; Kim, Won Bae; Choi, Eung Chil
Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 22 p. 5909 - 5915
