5-甲基-1-苯基-1H-吡唑-3-羧酸乙酯合成路线 （共 12 条）
反应条件
lithium hydroxide hydrate in ethylene glycol dimethyl ether T=20°C; 10 h; regioselective reaction;
参考文献
Sun, Aixue; Ye, Jia-Hai; Yu, Haitao; Zhang, Wenchao; Wang, Xiaolong
Tetrahedron Letters, 2014 , vol. 55, # 4 p. 889 - 892
反应条件
in octane T=110°C; 1 h;
参考文献
Padwa, Albert; Kulkarni, Yashwant S.; Zhang, Zhijia
Journal of Organic Chemistry, 1990 , vol. 55, # 13 p. 4144 - 4153
反应条件
sulfuric acid T=60°C; 24 h; regioselective reaction;
参考文献
Bonacorso, Helio G.; Correa, Michele S.; Porte, Liliane M.F.; Pittaluga, Everton P.; Zanatta, Nilo; Martins, Marcos A.P.
Tetrahedron Letters, 2012 , vol. 53, # 41 p. 5488 - 5491
反应条件
in toluene 3.5 h; Heating;
参考文献
Kashima, Choji; Shibata, Saori; Yokoyama, Hiroyo; Nishio, Takehiko
Journal of Heterocyclic Chemistry, 2003 , vol. 40, # 5 p. 773 - 782
反应条件
1.1: sodium hexamethyldisilazide / tetrahydrofuran / 0.5 h / -78 °C 1.2: 31 percent / tetrahydrofuran / 1.5 h / -78 - -40 °C 2.1: CDCl3 / 2 h / 100 °C / microwave irradiation View Scheme
参考文献
Organic Letters, , vol. 8, # 15 p. 3219 - 3222
反应条件
in chloroform-d1 T=100°C; 2 h; microwave irradiation;
参考文献
Organic Letters, , vol. 8, # 15 p. 3219 - 3222
反应条件
in ethanol 1 h; Reflux;
参考文献
Angewandte Chemie - International Edition, , vol. 49, # 15 p. 2790 - 2793
反应条件
in ethanol 3 h; Heating;
参考文献
Journal of Organic Chemistry, , vol. 68, # 15 p. 5977 - 5982
反应条件
1: 71 percent / POCl3, pyridine / 1) 0 deg C, 6 h, 2) r.t., 12 h 2: 87 percent / octane / 1 h / 110 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 55, # 13 p. 4144 - 4153
反应条件
4 h; Heating; Yield givenYields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of Heterocyclic Chemistry, , vol. 36, # 1 p. 217 - 220
