4-氨基-3,5-二氟苯乙酮合成路线 （共 3 条）
反应条件
1: With 1,3-bis-(diphenylphosphino)propane; potassium carbonate; palladium diacetate in DMF (N,N-dimethyl-formamide); water T=20 - 80°C; 24 h; 2: With formic acid; water in acetonitrile T=20°C; 0.75 h;
参考文献
WO2004/110997 A1, ;
Page 52-53 ;
WO 2004/110997 A1
反应条件
n-butyllithium T=-60 - -50°C;
参考文献
Asato, Goro; Baker, Pamela K.; Bass, Roy T.; Bentley, T. James; Chari, Sarangan; et al.
Agricultural and Biological Chemistry, 1984 , vol. 48, # 11 p. 2883 - 2888
反应条件
1: 85 percent / Br2 / acetic acid 2: 74 percent / BuLi / -60 - -50 °C View Scheme
参考文献
Agricultural and Biological Chemistry, , vol. 48, # 11 p. 2883 - 2888
