1-(4-氨基-苯基)-环丁烷甲腈合成路线 （共 2 条）
反应条件
1: potassium nitrate; sulfuric acid / 0 °C
2: 5 palladium on charcoal; hydrogen / methanol / 3 h / 60 °C / 2327.23 - 2585.81 Torr
View Scheme
参考文献
Shavnya, Andrei; Tao, Yong; Lilley, Susan C.; Bahnck, Kevin B.; Munchhof, Michael J.; Nematalla, Asaad; Waldo, Michael; Bill, David R.
Organic Process Research and Development, 2013 , vol. 17, # 12 p. 1510 - 1516
反应条件
1: potassium carbonate; tetrabutylammomium bromide / acetone / 20 h / 55 °C / |Large scale
2: 5 palladium on charcoal; hydrogen / methanol / 3 h / 60 °C / 2327.23 - 2585.81 Torr
View Scheme
参考文献
Shavnya, Andrei; Tao, Yong; Lilley, Susan C.; Bahnck, Kevin B.; Munchhof, Michael J.; Nematalla, Asaad; Waldo, Michael; Bill, David R.
Organic Process Research and Development, 2013 , vol. 17, # 12 p. 1510 - 1516
