10,11-亚甲二氧基-N-丙基去甲阿朴啡合成路线 （共 6 条）
反应条件
hydrogen; palladium on activated charcoal in acetic acid
T=40°C; 48 h;
参考文献
Ram, Vishnu J.; Neumeyer, John L.
Journal of Organic Chemistry, 1981 , vol. 46, # 13 p. 2830 - 2831
反应条件
sodium hydroxide in dimethyl sulfoxide
参考文献
Ram, Vishnu J.; Neumeyer, John L.
Journal of Organic Chemistry, 1981 , vol. 46, # 13 p. 2830 - 2831
反应条件
1: aq. NaOH / dimethylsulfoxide / 3 h / 70 - 80 °C
2: NaOH / acetonitrile / 30 h / Heating
View Scheme
参考文献
Ram, Vishnu J.; Neumeyer, John L.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1988 , vol. 27, # 1-12 p. 947 - 949
反应条件
sodium hydroxide in acetonitrile
30 h; Heating;
参考文献
Ram, Vishnu J.; Neumeyer, John L.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1988 , vol. 27, # 1-12 p. 947 - 949
反应条件
hydrogenchloride; sodium cyanoborohydride in ethanol
pH 3-5; Yield given;
参考文献
Ram, Vishnu J.; Neumeyer, John L.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1988 , vol. 27, # 1-12 p. 947 - 949
反应条件
in dimethyl sulfoxide
1.) 10 deg C, 2 h, 2.) 75-80 deg C, 4 h;
参考文献
Ram, Vishnu J.; Neumeyer, John L.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1988 , vol. 27, # 1-12 p. 947 - 949
