1-Boc-4-环戊基氨基-哌啶合成路线 (共 2 条)
反应条件
1: in methanol
T=20°C; 18 h;
2: With sodium tetrahydroborate
6 h;
参考文献
PFIZER LIMITED; PFIZER INC.
Patent: WO2004/111003 A1, 2004 ;
Location in patent: Page 63-64 ;
WO 2004/111003 A1
反应条件
sodium tris(acetoxy)borohydride; acetic acid in 1,2-dichloro-ethane
T=25°C;
参考文献
Bourdonnec, Bertrand Le; Leister, Lara K.; Ajello, Christopher A.; Cassel, Joel A.; Seida, Pamela R.; O'Hare, Heather; Gu, Minghua; Chu, Guo-Hua; Tuthill, Paul A.; DeHaven, Robert N.; Dolle, Roland E.
Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 1 p. 336 - 343