(三氟甲基)三甲基硅烷合成路线 （共 455 条）
反应条件
1-methyl-pyrrolidin-2-one; potassium fluoride; copper(l) iodide T=50°C; 20 h;
参考文献
Tetrahedron, , vol. 60, # 51 p. 11869 - 11874
反应条件
potassium fluoride; silver trifluoromethanesulfonate in 1,2-dichloro-ethane T=85°C; 24 h; Inert atmosphereDarkness;
参考文献
Organic Letters, , vol. 13, # 20 p. 5464 - 5467
反应条件
1: (trifluoromethyl)-trimethylsilane With N-methyl-pyrrolidine; potassium fluoride; copper(l) iodide T=50°C; 1.16667 h; Heating / reflux; 2: 2,5-dichloro-4-iodo-pyridine 20 h; 3: With ammonia; water
参考文献
SUMITOMO CHEMICAL COMPANY, LIMITED
Patent: WO2009/66786 A1, 2009 ;
Location in patent: Page/Page column 120-121 ;
反应条件
1: With potassium carbonate in N,N-dimethyl-formamide T=20°C; 4 h; 2: With water in N,N-dimethyl-formamide 4 h; Acidic conditions;
参考文献
Cheng, Huicheng; Pei, Yu; Leng, Faqiang; Li, Jingya; Liang, Apeng; Zou, Dapeng; Wu, Yangjie; Wu, Yusheng
Tetrahedron Letters, 2013 , vol. 54, # 33 p. 4483 - 4486
反应条件
[Pd(η3-1-Ph-allyl)(μ-Cl)]2; cyclohexyl BrettPhos; sodium lauryl sulfate; cesium fluoride in toluene T=110°C; 12 h; Inert atmosphere;
参考文献
Samant, Bhupesh S.; Kabalka, George W.
Chemical Communications, 2011 , vol. 47, # 25 p. 7236 - 7238
反应条件
1: MeCOO-BDT With copper(I) isothiocyanate; sodium isothiocyanate; caesium carbonate in acetonitrile T=20°C; 0.166667 h; Inert atmosphere; 2: (trifluoromethyl)-trimethylsilane in acetonitrile T=20°C; 16 h;
参考文献
Danoun, Gregory; Bayarmagnai, Bilguun; Gruenberg, Matthias F.; Goossen, Lukas J.
Chemical Science, 2014 , vol. 5, # 4 p. 1312 - 1316
反应条件
potassium phosphate; 1,10-phenanthroline; copper(I) isothiocyanate; sulfur; silver carbonate in N,N-dimethyl-formamide T=20°C; 24 h; Molecular sieveInert atmosphere;
参考文献
Chen, Chao; Xie, Yan; Chu, Lingling; Wang, Ruo-Wen; Zhang, Xingang; Qing, Feng-Ling
Angewandte Chemie - International Edition, 2012 , vol. 51, # 10 p. 2492 - 2495
反应条件
1: With potassium carbonate in N,N-dimethyl-formamide T=20°C; 4 h; 2: With water in N,N-dimethyl-formamide 4 h; Acidic conditions;
参考文献
Cheng, Huicheng; Pei, Yu; Leng, Faqiang; Li, Jingya; Liang, Apeng; Zou, Dapeng; Wu, Yangjie; Wu, Yusheng
Tetrahedron Letters, 2013 , vol. 54, # 33 p. 4483 - 4486
反应条件
potassium fluoride; potassium phosphate; 1,10-phenanthroline; copper (I) trifluoromethane sulfonate benzene; silver carbonate in N,N-dimethyl-formamide T=45°C; Inert atmosphere;
参考文献
Chu, Lingling; Qing, Feng-Ling
Organic Letters, 2010 , vol. 12, # 21 p. 5060 - 5063
反应条件
1: (trifluoromethyl)-trimethylsilane With copper(I) isothiocyanate; caesium carbonate in acetonitrile T=20°C; 0.166667 h; Inert atmosphere; 2: MeCOO-BDT in acetonitrile T=20°C; Sandmeyer Reaction; 16 h; Inert atmosphere;
参考文献
Danoun, Gregory; Bayarmagnai, Bilguun; Gruenberg, Matthias F.; Goossen, Lukas J.
Angewandte Chemie - International Edition, 2013 , vol. 52, # 31 p. 7972 - 7975
Angew. Chem., 2013 , vol. 125, # 31 p. 8130 - 8133
