(三氟甲基)三甲基硅烷合成路线 （共 455 条）
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran T=0°C; 0.0166667 h;
参考文献
Journal of the Chemical Society. Perkin Transactions 1, , # 11 p. 1256 - 1257
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran
参考文献
Yoshimatsu, Mitsuhiro; Kuribayashi, Masako
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 11 p. 1256 - 1257
反应条件
potassium fluoride; copper(l) iodide in 1-methyl-pyrrolidin-2-one; N,N-dimethyl-formamide T=20°C; 16 h;
参考文献
NOVARTIS AG; NOVARTIS PHARMA GMBH
Patent: WO2006/136442 A1, 2006 ;
Location in patent: Page/Page column 92-93 ;
WO 2006/136442 A1
反应条件
potassium fluoride; copper(l) iodide in N,N-dimethyl-formamide T=25°C; 18 h;
参考文献
KALYPSYS, INC.
Patent: WO2009/117421 A2, 2009 ;
Location in patent: Page/Page column 86 ;
WO 2009/117421 A2
反应条件
potassium fluoride; silver trifluoromethanesulfonate in 1,2-dichloro-ethane T=85°C; 24 h; Inert atmosphereDarkness;
参考文献
Ye, Yingda; Lee, Shin Hee; Sanford, Melanie S.
Organic Letters, 2011 , vol. 13, # 20 p. 5464 - 5467
反应条件
cesium fluoride in acetonitrile T=20°C; 22 h;
参考文献
Stanek, Kyrill; Koller, Raffael; Togni, Antonio
Journal of Organic Chemistry, 2008 , vol. 73, # 19 p. 7678 - 7685
反应条件
cesium fluoride in acetonitrile T=20°C; 15 h;
参考文献
Eisenberger, Patrick; Gischig, Sebastian; Togni, Antonio
Chemistry - A European Journal, 2006 , vol. 12, # 9 p. 2579 - 2586
反应条件
potassium fluoride; copper(l) iodide in 1-methyl-pyrrolidin-2-one; N,N-dimethyl-formamide T=25°C; 6 h;
参考文献
Cottet, Fabrice; Schlosser, Manfred
European Journal of Organic Chemistry, 2002 , # 2 p. 327 - 330
反应条件
1: (trifluoromethyl)-trimethylsilane With 1-methyl-pyrrolidin-2-one; potassium fluoride; copper(l) iodide T=50°C; 0.5 h; 2: 3-chloro-4-iodopyridine T=50°C; 20 h; Further stages.;
参考文献
Cottet, Fabrice; Schlosser, Manfred
European Journal of Organic Chemistry, 2004 , # 18 p. 3793 - 3798
反应条件
potassium fluoride; potassium phosphate; 1,10-phenanthroline; copper (I) trifluoromethane sulfonate benzene; silver carbonate in N,N-dimethyl-formamide T=45°C; Inert atmosphere;
参考文献
Chu, Lingling; Qing, Feng-Ling
Organic Letters, 2010 , vol. 12, # 21 p. 5060 - 5063
