(三氟甲基)三甲基硅烷合成路线 （共 455 条）
反应条件
tetramethyl-ammonium fluoride in ethylene glycol dimethyl ether T=-30 - 20°C;
参考文献
Babadzhanova; Kirij; Yagupolskii; Tyrra; Naumann
Tetrahedron, 2005 , vol. 61, # 7 p. 1813 - 1819
反应条件
potassium fluoride; copper(l) iodide; silver tetrafluoroborate; 3,4,7,8-tetra-methyl-1,10-phenanthroline; silver fluoride in N,N-dimethyl-formamide T=80°C; 24 h; GloveboxInert atmosphere;
参考文献
Xu, Jun; Xiao, Bin; Xie, Chuan-Qi; Luo, Dong-Fen; Liu, Lei; Fu, Yao
Angewandte Chemie - International Edition, 2012 , vol. 51, # 50 p. 12551 - 12554
Angew. Chem., 2012 , vol. 124, # 50 p. 12719 - 12722,4
反应条件
[bis(acetoxy)iodo]benzene; silver fluoride in dimethyl sulfoxide T=20°C; 20 h;
参考文献
Chemical Communications, , vol. 49, # 57 p. 6385 - 6387
反应条件
1: (trifluoromethyl)-trimethylsilane With silver monofluoride T=20°C; 2 h; 2: furan-2-carbonyl chloride With 4-(N,N-dimethlyamino)pyridine in dichloromethane T=20°C; 48 h; Further stages.;
参考文献
Kremlev, Mikhail M.; Mushta, Aleksej I.; Tyrra, Wieland; Naumann, Dieter; Fischer, Hendrik T.M.; Yagupolskii, Yurii L.
Journal of Fluorine Chemistry, 2007 , vol. 128, # 11 p. 1385 - 1389
反应条件
boron tribromide T=-25 - 20°C;
参考文献
Levin, Vitalij V.; Dilman, Alexander D.; Belyakov, Pavel A.; Struchkova, Marina I.; Tartakovsky, Vladimir A.
Journal of Fluorine Chemistry, 2009 , vol. 130, # 7 p. 667 - 670
反应条件
potassium fluoride; copper monoiodide in diethyl ether; ethyl acetate; N,N-dimethyl-formamide
参考文献
Wyeth
Patent: EP1137645 B1, 2004 ;
Location in patent: Page 32 ;
反应条件
potassium fluoride; copper(l) iodide in 1-methyl-pyrrolidin-2-one; N,N-dimethyl-formamide T=25°C; 6 h;
参考文献
Cottet, Fabrice; Schlosser, Manfred
European Journal of Organic Chemistry, 2002 , # 2 p. 327 - 330
反应条件
1: C13H20N4O2 With methyl iodide T=110°C; Inert atmosphere; 2: (trifluoromethyl)-trimethylsilane With potassium fluoride; copper(l) iodide in 1-methyl-pyrrolidin-2-one T=60°C; 16 h; Inert atmosphere;
参考文献
Hafner, Andreas; Braese, Stefan
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 5 p. 996 - 1000
反应条件
1: With potassium carbonate in N,N-dimethyl-formamide T=20°C; 4 h; 2: With tetrabutyl ammonium fluoride in N,N-dimethyl-formamide 4 h;
参考文献
Tetrahedron Letters, , vol. 54, # 33 p. 4483 - 4486
反应条件
1: With potassium carbonate in N,N-dimethyl-formamide T=20°C; 4 h; 2: With water in N,N-dimethyl-formamide 4 h; Acidic conditions;
参考文献
Cheng, Huicheng; Pei, Yu; Leng, Faqiang; Li, Jingya; Liang, Apeng; Zou, Dapeng; Wu, Yangjie; Wu, Yusheng
Tetrahedron Letters, 2013 , vol. 54, # 33 p. 4483 - 4486
