(三氟甲基)三甲基硅烷合成路线 （共 455 条）
反应条件
1: With potassium carbonate in N,N-dimethyl-formamide
T=20°C; 4 h;
2: With water in N,N-dimethyl-formamide
4 h; Acidic conditions;
参考文献
Cheng, Huicheng; Pei, Yu; Leng, Faqiang; Li, Jingya; Liang, Apeng; Zou, Dapeng; Wu, Yangjie; Wu, Yusheng
Tetrahedron Letters, 2013 , vol. 54, # 33 p. 4483 - 4486
反应条件
1,10-phenanthroline; di-tert-butyl peroxide; copper diacetate; sodium acetate; sodium t-butanolate in 1,2-dichloro-ethane
T=80°C; 6.03333 h; Inert atmosphereMolecular sieve;
参考文献
Chu, Lingling; Qing, Feng-Ling
Journal of the American Chemical Society, 2012 , vol. 134, # 2 p. 1298 - 1304
反应条件
tris(dimethylamino)-sulphonium difluorotrimethylsilicate in tetrahydrofuran
30 min at -25 deg C, then slowly warmed up to 10 deg C (total time 2 h);
参考文献
Movchun, Valeria N.; Kolomeitsev, Alexander A.; Yagupolskii, Yurii L.
Journal of Fluorine Chemistry, 1995 , vol. 70, # 2 p. 255 - 258
反应条件
1: (trifluoromethyl)-trimethylsilane With silver fluoride in N,N-dimethyl-formamide
T=20°C; 0.333333 h;
2: With copper in N,N-dimethyl-formamide
4 h;
3: n-dodecyl iodide in N,N-dimethyl-formamide
参考文献
Kremlev, Mikhail M.; Mushta, Aleksej I.; Tyrra, Wieland; Yagupolskii, Yurii L.; Naumann, Dieter; Moeller, Angela
Journal of Fluorine Chemistry, 2012 , vol. 133, p. 67 - 71
反应条件
potassium fluoride; copper(l) iodide; N-(EtOCH2CH2OCH2)-N-methylmorpholinium bis(CF3SO2)amide
T=80°C; 8 h;
参考文献
Kim, Jinwi; Shreeve, Jean'ne M.
Organic and Biomolecular Chemistry, 2004 , vol. 2, # 19 p. 2728 - 2734
反应条件
1: (trifluoromethyl)-trimethylsilane With silver fluoride in anhydrous propionitrile
T=20°C; 0.333333 h;
2: With copper in anhydrous propionitrile
4 h;
3: 1-chloro-2,4-dinitro-benzene in anhydrous propionitrile
T=20°C; Heating;
参考文献
Kremlev, Mikhail M.; Mushta, Aleksej I.; Tyrra, Wieland; Yagupolskii, Yurii L.; Naumann, Dieter; Moeller, Angela
Journal of Fluorine Chemistry, 2012 , vol. 133, p. 67 - 71
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran
0 deg C, 1 h, RT;
参考文献
Billard, Thierry; Langlois, Bernard R.
Tetrahedron Letters, 1996 , vol. 37, # 38 p. 6865 - 6868
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran
0 deg C, 5 min then rt., 2.5 h;
参考文献
Billard, Thierry; Large, Sylvie; Langlois, Bernard R.
Tetrahedron Letters, 1997 , vol. 38, # 1 p. 65 - 68
反应条件
potassium fluoride; copper(l) iodide in 1-methyl-pyrrolidin-2-one; N,N-dimethyl-formamide
T=80°C; 41 h;
参考文献
Mano, Takashi; Stevens, Rodney W.; Ando, Kazuo; Nakao, Kazunari; Okumura, Yoshiyuki; Sakakibara, Minoru; Okumura, Takako; Tamura, Tetsuya; Miyamoto, Kimitaka
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 18 p. 3879 - 3887
反应条件
1,10-phenanthroline; di-tert-butyl peroxide; copper diacetate; sodium acetate; sodium t-butanolate in 1,2-dichloro-ethane
T=80°C; 6.03333 h; Inert atmosphereMolecular sieve;
参考文献
Chu, Lingling; Qing, Feng-Ling
Journal of the American Chemical Society, 2012 , vol. 134, # 2 p. 1298 - 1304
