(三氟甲基)三甲基硅烷合成路线 （共 455 条）
反应条件
1: C13H20ClN3 With methyl iodide
T=110°C; Inert atmosphere;
2: (trifluoromethyl)-trimethylsilane With potassium fluoride; copper(l) iodide in 1-methyl-pyrrolidin-2-one
T=60°C; 16 h; Inert atmosphere;
参考文献
Hafner, Andreas; Braese, Stefan
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 5 p. 996 - 1000
反应条件
1: With cesium fluoride in neat (no solvent)
T=20°C; Schlenk techniqueInert atmosphere;
2: With tetra-n-butylammonium fluoride trihydrate in neat (no solvent)
T=20°C; 2 h; Schlenk techniqueInert atmosphere;
参考文献
Wang, Yi; Yuan; Xing, Chun-Hui; Lu, Long
Tetrahedron Letters, 2014 , vol. 55, # 5 p. 1045 - 1048
反应条件
potassium fluoride in acetonitrile
18 h; -40 to 19 deg C;
参考文献
Kotun, Stefan P.; Anderson, John D. O.; DesMarteau, Darryl D.
Journal of Organic Chemistry, 1992 , vol. 57, # 4 p. 1124 - 1131
反应条件
tetra-n-butylammonium difluorotriphenylsilicate(IV) in tetrahydrofuran
T=0 - 10°C; 4 h; Inert atmosphere;
参考文献
Masusai, Chonticha; Soorukram, Darunee; Kuhakarn, Chutima; Tuchinda, Patoomratana; Reutrakul, Vichai; Pohmakotr, Manat
Journal of Fluorine Chemistry, 2013 , vol. 154, p. 37 - 42
反应条件
cesium fluoride in N,N-dimethyl-formamide
T=20°C; 0.5 h;
参考文献
Wang, Xi; Xu, Yan; Mo, Fanyang; Ji, Guojing; Qiu, Di; Feng, Jiajie; Ye, Yuxuan; Zhang, Songnan; Zhang, Yan; Wang, Jianbo
Journal of the American Chemical Society, 2013 , vol. 135, # 28 p. 10330 - 10333
反应条件
cesium fluoride in N,N-dimethyl-formamide
T=20°C; 0.5 h; Inert atmosphereGloveboxSchlenk technique;
参考文献
Wang, Xi; Xu, Yan; Mo, Fanyang; Ji, Guojing; Qiu, Di; Feng, Jiajie; Ye, Yuxuan; Zhang, Songnan; Zhang, Yan; Wang, Jianbo
Journal of the American Chemical Society, 2013 , vol. 135, # 28 p. 10330 - 10333
反应条件
potassium fluoride; copper(l) iodide; 1,10-phenanthroline; oxygen in N,N-dimethyl-formamide
T=100°C; P=760.051 Torr;
参考文献
Jiang, Xueliang; Chu, Lingling; Qing, Feng-Ling
Journal of Organic Chemistry, 2012 , vol. 77, # 3 p. 1251 - 1257
反应条件
sulfur; potassium fluoride in N,N-dimethyl-formamide
T=20°C; 6 h; Air;
参考文献
Chen, Chao; Chu, Lingling; Qing, Feng-Ling
Journal of the American Chemical Society, 2012 , vol. 134, # 30 p. 12454 - 12457
反应条件
potassium fluoride; copper(l) iodide in N,N-dimethyl-formamide
T=100°C;
参考文献
Chu, Lingling; Qing, Feng-Ling
Journal of the American Chemical Society, 2010 , vol. 132, # 21 p. 7262 - 7263
反应条件
1: 5-isobutylidene-2,2-dimethyl-[1,3]dioxan-4-one; (trifluoromethyl)-trimethylsilane With sodium acetate in N,N-dimethyl-formamide
T=50°C; 2 h; Inert atmosphere;
2: With hydrogenchloride in water; N,N-dimethyl-formamide
T=120°C; 1 h; Inert atmosphere;
3: benzyl bromide With potassium carbonate in N,N-dimethyl-formamide
T=20°C; 2 h; Inert atmosphere;
参考文献
Zemtsov, Artem A.; Levin, Vitalij V.; Dilman, Alexander D.; Struchkova, Marina I.; Belyakov, Pavel A.; Tartakovsky, Vladimir A.
Tetrahedron Letters, 2009 , vol. 50, # 25 p. 2998 - 3000
