(三氟甲基)三甲基硅烷合成路线 （共 455 条）
反应条件
1-methyl-pyrrolidin-2-one; potassium fluoride; copper(l) iodide
Heating;
参考文献
Cottet, Fabrice; Schlosser, Manfred
Tetrahedron, 2004 , vol. 60, # 51 p. 11869 - 11874
反应条件
lithium iodide in triglyme (triethylene glycol dimethyl ether)
T=170°C; 1.5 h; Inert atmosphereMicrowave irradiation; Reagent/catalystSolventTemperatureTime;
参考文献
Surya Prakash; Krishnamoorthy, Sankarganesh; Ganesh, Somesh K.; Kulkarni, Aditya; Haiges, Ralf; Olah, George A.
Organic Letters, 2014 , vol. 16, # 1 p. 54 - 57
反应条件
potassium fluoride; 1,10-phenanthroline; copper diacetate; silver carbonate
参考文献
Cernova, Miroslava; Pohl, Radek; Klepetarova, Blanka; Hocek, Michal
Heterocycles, 2014 , vol. 89, # 5 p. 1159 - 1171
反应条件
[Ph3SnF2][NBu4] in dichloromethane
T=0°C; 1 h; Yield given;
参考文献
Portella, Charles; Brigaud, Thierry; Lefebvre, Olivier; Plantier-Royon, Richard
Journal of Fluorine Chemistry, 2000 , vol. 101, # 2 p. 193 - 198
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran; pentane
24 h; Ambient temperature;
参考文献
Wiedemann, Juergen; Heiner, Thomas; Mloston, Gregorz; Prakash, G.K. Surya; Olah, George A.
Angewandte Chemie - International Edition, 1998 , vol. 37, # 6 p. 820 - 821
反应条件
1: (trifluoromethyl)-trimethylsilane With silver monofluoride in various solvent(s)
T=20°C; 2 h;
2: (2E)-3-phenylprop-2-enoyl chloride in various solvent(s)
T=20°C; 12 h; Further stages.;
参考文献
Kremlev, Mikhail M.; Mushta, Aleksej I.; Tyrra, Wieland; Naumann, Dieter; Fischer, Hendrik T.M.; Yagupolskii, Yurii L.
Journal of Fluorine Chemistry, 2007 , vol. 128, # 11 p. 1385 - 1389
反应条件
1: With tetra-n-butylammonium acetate in toluene
T=0 - 20°C; 1 h;
2: With hydrogenchloride in tetrahydrofuran; toluene
参考文献
Kawano, Yoshikazu; Kaneko, Nobuya; Mukaiyama, Teruaki
Bulletin of the Chemical Society of Japan, 2006 , vol. 79, # 7 p. 1133 - 1145
反应条件
copper(l) iodide; silver fluoride; sodium t-butanolate; N-methyl-2-(methylamino)ethylamine in 1-methyl-pyrrolidin-2-one
T=20 - 90°C; 5.5 h; Inert atmosphere;
参考文献
Weng, Zhiqiang; Lee, Richmond; Jia, Weiguo; Yuan, Yaofeng; Wang, Wenfeng; Feng, Xue; Huang, Kuo-Wei
Organometallics, 2011 , vol. 30, # 11 p. 3229 - 3232
反应条件
potassium fluoride; silver trifluoromethanesulfonate in 1,2-dichloro-ethane
T=85°C; 24 h; Inert atmosphereDarkness;
参考文献
Ye, Yingda; Lee, Shin Hee; Sanford, Melanie S.
Organic Letters, 2011 , vol. 13, # 20 p. 5464 - 5467
反应条件
1: C14H20N4 With methyl iodide
T=110°C; 5 h; Inert atmosphere;
2: (trifluoromethyl)-trimethylsilane With potassium fluoride; copper(l) iodide in 1-methyl-pyrrolidin-2-one
T=60°C; 16 h; Inert atmosphere; Reagent/catalyst;
参考文献
Hafner, Andreas; Braese, Stefan
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 5 p. 996 - 1000
