(三氟甲基)三甲基硅烷合成路线 （共 455 条）
反应条件
1: in tetrahydrofuran
T=0°C; 0.166667 h; Inert atmosphereSealed tube;
2: With tetrabutyl ammonium fluoride in tetrahydrofuran
T=0 - 20°C; Inert atmosphereSealed tube;
3: With tetrabutyl ammonium fluoride; water in tetrahydrofuran
T=0 - 20°C; Inert atmosphereSealed tube;
参考文献
Kelly, Christopher B.; Mercadante, Michael A.; Hamlin, Trevor A.; Fletcher, Madison H.; Leadbeater, Nicholas E.
Journal of Organic Chemistry, 2012 , vol. 77, # 18 p. 8131 - 8141
反应条件
1: With tetrabutyl ammonium fluoride in tetrahydrofuran
T=0 - 20°C; 3.25 h;
2: With hydrogenchloride in tetrahydrofuran; water
1 h;
参考文献
APPLERA CORPORATION
Patent: WO2006/102535 A2, 2006 ;
Location in patent: Page/Page column 75-76 ;
WO 2006/102535 A2
反应条件
1: With 4 A molecular sieve; tetrabutyl ammonium fluoride in tetrahydrofuran; pentane
T=-78 - 20°C;
2: With sodium hydrogencarbonate in tetrahydrofuran; pentane
T=0°C; Further stages.;
参考文献
Funabiki, Kazumasa; Shibata, Akitsugu; Iwata, Hiroki; Hatano, Keisuke; Kubota, Yasuhiro; Komura, Kenichi; Ebihara, Masahiro; Matsui, Masaki
Journal of Organic Chemistry, 2008 , vol. 73, # 12 p. 4694 - 4697
反应条件
lithium iodide in triglyme (triethylene glycol dimethyl ether)
T=170°C; 1.5 h; Inert atmosphereMicrowave irradiation; Time;
参考文献
Surya Prakash; Krishnamoorthy, Sankarganesh; Ganesh, Somesh K.; Kulkarni, Aditya; Haiges, Ralf; Olah, George A.
Organic Letters, 2014 , vol. 16, # 1 p. 54 - 57
反应条件
1: With potassium carbonate in N,N-dimethyl-formamide
T=20°C; 4 h;
2: With water in N,N-dimethyl-formamide
4 h; Acidic conditions;
参考文献
Cheng, Huicheng; Pei, Yu; Leng, Faqiang; Li, Jingya; Liang, Apeng; Zou, Dapeng; Wu, Yangjie; Wu, Yusheng
Tetrahedron Letters, 2013 , vol. 54, # 33 p. 4483 - 4486
反应条件
1: With tetrabutyl ammonium fluoride in tetrahydrofuran
T=0 - 20°C; 0.583333 h;
2: With hydrogenchloride in tetrahydrofuran; water
T=20°C; 5 h;
参考文献
The United States of America as represented by the Secretary of the Navy
Patent: US7189867 B1, 2007 ;
Location in patent: Page/Page column 5-6 ;
反应条件
potassium fluoride; silver trifluoromethanesulfonate in 1,2-dichloro-ethane
T=85°C; 24 h; Inert atmosphereDarkness;
参考文献
Ye, Yingda; Lee, Shin Hee; Sanford, Melanie S.
Organic Letters, 2011 , vol. 13, # 20 p. 5464 - 5467
反应条件
hydrogenchloride; tetrabutyl ammonium fluoride in tetrahydrofuran
参考文献
Liu, Qingyun; Zambrowicz, Brian
Patent: US2009/29993 A1, 2009 ;
US 20090029993 A1
反应条件
hydrogenchloride; tetrabutyl ammonium fluoride in tetrahydrofuran
参考文献
Brown, Philip Manton; Liu, Qingyun
Patent: US2009/5382 A1, 2009 ;
US 20090005382 A1
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran
0 deg C, 1 h, RT;
参考文献
Billard, Thierry; Langlois, Bernard R.
Tetrahedron Letters, 1996 , vol. 37, # 38 p. 6865 - 6868
