2-[(三甲基硅烷基)甲基]-2-丙烯-1-醇合成路线 （共 15 条）
反应条件
pyridine in dichloromethane T=0°C; 0.666667 h;
参考文献
Trost,B.M.; Renaut,P.
Journal of the American Chemical Society, 1982 , vol. 104, p. 6668
反应条件
1: 91 percent / N,N,N',N'-tetramethylene diamine, n-C4H9Li / tetrahydrofuran / -60 °C 2: 1) H2SO4, 2) nC4H9Li / 1) water, THF, RT, 2) THF, -6 deg C View Scheme
参考文献
Trost, Barry M.; Mignani, Serge M.; Nanninga, Thomas N.
Journal of the American Chemical Society, 1986 , vol. 108, # 19 p. 6051 - 6053
反应条件
pyridine; thionyl chloride in dichloromethane 0.5 h; Ambient temperature;
参考文献
Jones, Michael D.; Kemmitt, Raymond D. W.; Platt, Andrew W. G.
Journal of the Chemical Society, Dalton Transactions: Inorganic Chemistry (1972-1999), 1986 , p. 1411 - 1418
反应条件
sulfuric acid in tetrahydrofuran
0.5 h; Ambient temperature;
参考文献
Trost,B.M.; Renaut,P.
Journal of the American Chemical Society, 1982 , vol. 104, p. 6668
反应条件
n-butyllithium; oxonium
Multistep reaction;
参考文献
Krafft; Garcia; Guram; et al.
Tetrahedron Letters, 1986 , vol. 27, # 24 p. 2691 - 2694
反应条件
oxygen O2, singlet in methanol
T=40°C; 11 h; Irradiation; Title compound not separated from byproducts;
参考文献
Dubac, J.; Laporterie, A.; Iloughmane, H.; Pillot, J. P.; Deleris, G.; Dunogues, J.
Journal of Organometallic Chemistry, 1985 , vol. 281, p. 149 - 162
反应条件
cerium(III) chloride
参考文献
Lee, Thomas V.; Porter, John R.; Roden, Frances S.
Tetrahedron Letters, 1988 , vol. 29, # 39 p. 5009 - 5012
反应条件
in hexane
T=5 - 20°C; 0.75 h; Yield given;
参考文献
Agnel, Gilbert; Malacria, Max
Synthesis, 1989 , # 9 p. 687 - 688
反应条件
ethylmagnesium bromide; copper(I) bromide
1.) ether, -10 deg C 2.) ether, -10 deg C to R.T., 26 h; Yield given. Multistep reaction;
参考文献
Foulon, J. P.; Bourgain-Commercon, M.; Normant, J. F.
Tetrahedron, 1986 , vol. 42, # 5 p. 1389 - 1398
反应条件
n-butyllithium; bis(1,3-diphenylphosphinopropane) nickel(II) chloride
1.) THF, hexane, 0 deg C, 10 min, 2.) reflux, 3 h; Yield given. Multistep reaction;
参考文献
Organ, Michael G.; Murray, Aaron P.
Journal of Organic Chemistry, 1997 , vol. 62, # 5 p. 1523 - 1526
