3-氰基-1-甲基-1H-吡唑-4-羧酸合成路线 （共 2 条）
反应条件
1: With 1,1'-bis-(diphenylphosphino)ferrocene; sodium acetate; palladium diacetate in methanol
T=120°C; P=7500.75 Torr;
2: With water; sodium hydroxide in tetrahydrofuran; methanol
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH; FLECK, Martin; HEIMANN, Annekatrin; HEINE, Niklas; NOSSE, Bernd; ROTH, Gerald Juergen
Patent: WO2014/56771 A1, 2014 ;
Location in patent: Page/Page column 98; 99 ;
反应条件
1: palladium diacetate; 1,1'-bis-(diphenylphosphino)ferrocene; sodium acetate / methanol / 120 °C / 7500.75 Torr
2: water; sodium hydroxide / tetrahydrofuran; methanol / 20 °C
View Scheme
参考文献
Boehringer Ingelheim International GmbH; FLECK, Martin; HEINE, Niklas; NOSSE, Bernd; ROTH, Gerald Juergen
Patent: US2014/100211 A1, 2014 ;
